Chlorogenic acid. Features iyo guryaha lagmamaarmaanna

Coffee jacayl by dadka intooda badan ay dhadhan iyo saamayn tonic, laakiin kuwo yar ogahay in doorka ugu muhiimsan ee this cabitaan aad u caan ah oo door ah oo ay acid chlorogenic Halabuurka. The sifooyinka xarunta kiimikada siiyey waxaa inta badan la aasaasay uugu caraf cokan iyo dhadhanka la safeeyey, waxaa sidaas u bogi taageerayaasha ay tiro badan. Intaa waxaa dheer, walaxda, sida lagu sheegay cilmi baaris ugu dambeeyey ee jidhkeena si faa'iidooyin badan noolaha iyo nafeedba u keenaya. Si kastaba ha ahaatee, waxyaalihii hore marka hore.

Marka laga eego dhnaca ee kimistari organic chlorogenic acid waa esterified leh kafeyn depsides hydroxyl, at eb carbon saddexaad quinic acid taagan. xarunta kiimikada Tani waxa ay joogtaa dhirta badan, laakiin waxa ugu muhiimsan waa in miraha bunka sababtoo ah heerka aan caadi ahayn ka. Waxaa ku jira oo ku saabsan toddoba boqolkiiba chlorogenic acid. Dhawaan waxaa lagu ogaaday in il wanaagsan ee ay walax this shaqayn karo Eucommia baxo - geed kaymo gaarey height ah labaatan mitir.

Chlorogenic acid uu leeyahay shaqo muhiim ah in geeddi enzymatic iyo murqo kala duwan unugyada dhirta. Laakiin jidhkeenna, sidoo kale waxaa wax badan oo ka mid ah faa'iidooyinka keenaa. Chlorogenic acid waa wax ku ool ah iyo gubashadii baruurta ammaan ah, waxaa ku caawinaysa in ay helaan tirada a caato ah. Dheeraad ah, xarunta this kiimikada hagaajinaysaa geeddi socodka dheefshiidka ee beerka, taas oo qabata shaqo muhiim ah oo qaybsama dufanka dhacaya jidhkeena gudahooda. Chlorogenic acid kale oo uu leeyahay gacanta ku heerarka sonkorta dhiigga qaarkood.

Waa acid this waa awoodaa inuu badalo xawaaraha degdegsiimada dukaamada baruur xad-dhaaf ah ee tamar nadiif ah, kuwaas oo si gaar ah muhiim u ah dadka doonaya in ay lumiyaan miisaan. Muuqaal kale ee wax this u faa'iido badan tahay awooddiisa ah inuu hoos u dhigi habka dheefshiidka carbohydrate, kaas oo sidoo kale lagu shubi karaa jirka ka mid ah meelaha dhibaatada (bowdyaha, caloosha, oo xanjaadka) sidii xaydhii.

Chlorogenic acid markii ugu horaysay la helay by botanist Ruushka iyo A.S.Famintsynym deeqbixiye ee 1893 on qaybaha cotyledons gabbaldayaha iyada oo dareen-celin tayo micro-kiimikada. Qaybinta baahsan ee xarunta kiimikada this ka mid ah dhirta sare (Waxaa la ogaaday in 98 mi ah 230-daqiiqadii baarka bartay) soo jiidatay dadkii ugu saynisyahano waxay bilaabeen inay bartaan doorkeeda noolaha ee horumarinta iyo nolosha noolaha dhirta.

Sidaas darteed, waxaa la ogaaday in chlorogenic acid (si ay u iibsadaan waxaa lagu samaysan karin qaab saafi ah, kuna waari dhexdeeda waa budo cad crystalline) waxaa si firfircoon uga qayb sharciyeynta geedi socodka koriinkedu uurjiifka, ku simaha sida inhibitor ah phosphorylation murqo. Waxaa kale oo la og yahay in xarunta kiimikada waa mid aad u sun ah in noocyada qaar ka mid ah sheyga pathogenic keeni cuduro badan oo kala duwan ee dhirta. Tusaale ahaan, korodhka bariiska ee biosynthesis acid chlorogenic adeegtaa sida jawaab dabiiciga ah si ay cudurka microbial.

Ma muddo dheer ka hor, saynisyahano Chinese ayaa sameeyey daahfurka caafimaad oo muhiim ah. Ka dib markii taxane ah oo waxbarashada waxay ka heli in walaxda bayoloji firfircoon, si ay awood u gaar ah si loo joojiyo borotiinada sun mahad, awood u leh in ay noqdaan ku salaysan daawo ka hortagga iyo daaweynta sonkorowga mellitus.