BIMF - New Technology qaadashada Gabowga

Qaybta cilmiyeed iyo farsamo

Xaq Mabda'a of noolaha-shaqsi

technology Medical (BIMF)

Marka qoraal qaybtan, dhibaatada soo food by qoraaga, afka iyo waxa la eego si ay u sameeyaan bandhigga. Waxaa la go'aansaday in ay sharaxaad ka

ugu fudud, sababtoo ah BIMF ka mid ah noocyo kala duwan oo teknoolajiyada, iyo war qoraal ah oo ku saabsan wax kasta oo "isku af warshadaha" ka dhigi kartaa faahfaahinta dahsoon iyo xirfadlayaasha kale.

La soo jeediyay technology BIMF muhiim ugu horrayn sida a-daweynta farsamada sababta oo ah boqolaal nooc oo ah ogaanshaha nidaamka yahay ma la daaweyn lahayn mid.

1. mabaadiida aasaasiga ah iyo dhaleecayn.

Waa in la ogaadaa, in our opinion, qodobada muhiimka ah ee raadinta

Nin ka mid ah mabaadi'da iyo hab daaweyn caafimaad. Waayo, kuwa yaa garan noqon kartaa caajiso, laakiin weli aad ugu yeerto sida ay ahayd.

Ka hor dhalashada of antibiotics, ka dibna markii ay muuqan aadanaha

rajaynayeen inay haystaan oo ay isticmaalaan ee "ugu fiican" macnaheedu waa in,

Waxa ay u muuqatay ku saabsan in la furay. Qof walba sugayay nooc ka mid ah "rasaas sixir"

(Ehrlich). Dheeraad ah, ku dul ogaanshaha iska caabin ah sheyga in ay

antibiotics, rayn siiyey si ay amardiiddo. Marka saynisyahano waqti isku mid ah

sameeyey "immersion" labaad ee daawada dabiiciga ah iyo waxyaabaha dabiiciga ah

(Hooyo, carjawda shark, Chaga, iyo geedo yaryar ajuurada) in isku day ah si aad u hesho a dabiiciga cajiibka ah

ka dhigan tahay. Horumarinta ee genetics iyo proteomics daahfurka ee antioksidanter,

ogaanshaha of walxaha bayoloji-firfircoon oo badan, receptors ay, horumarinta dawooyin kiimiko awood u muuqatay tusayo si ka soo Farmashiiste ku cakirnaanta af iyo qoraal iyo daawo. Dabcan, guulaha ay gaadhay in daaweynta muxaafidka ah ee cudurada qaar ka mid ah, qofna ma beenisay. Si kastaba ha ahaatee, guulaha kuwanu ma ku filan.

Deciphering hiddawadayaasha aadanaha ayay koreen oo yar. daroogada Avv halis ma daaweeyaan AIDS. Xitaa 30-35 kun oo hiddo-ee hiddawadayaasha aadanaha siiyaan fursadaha iyo isku dhow dhammaadka lahayn, xitaa aragti ahaan macquul aheyn si ay u xisaabiso daraasadda of function hiddo iyo fursadaha dhexgalka ay.

Sababta failure in daaweynta kansarka iyo cudurada kale ee been polymorphism (tirayn) genomes Kiimikada noole protein. No, xataa kuwa ugu fiican, sida uu abuuray, daroogada marnaba run ahaantii in uu 100% ee "Kiimikada noole" jidhka bukaan gaar ah, sababta oo ah "ay Kiimikada noole u gaar ah" iyo "genetics u gaar ah", gaar isaga. Sidee bay u kala duwan yihiin min qof ilaa qof? Jawaabtu waa: fog sida qof ayaa mid kasta oo kala duwan ka soo midba midka kale. Waxaa jiray isku dayo in la isticmaalo uurjiifka, therapy SNMna, iyo ugu dambeyntii stem cells - "universal" noolaha (cell, tissue) therapy.

In isku midka ah, si kastaba ha ahaatee, waxa uu ahaa horumarinta daawo shakhsi.

Oo waxay noqotay in jajabkii. homeopathy loo isticmaalo hordhaca ah ee dhiig isaga u gaar ah (autohemotherapy), waxaa la aasaasay (loola dhaqmo sida) (Samuel Hahnemann), mabaadi'da ay la isticmaalay doorashada ee shaqsinimo

daawooyinka homoeopathic (adag si gaar ah) iyo soo saaridda of noocyo ka mid ah daroogada (nosodes, renozody) wax (tissue buka) ee bukaanka shaqsi. Diyaarinta qalab shakhsi nafleyda (dheecaanka, dhiig) bukaanka (habka of L. Yaschenko, Crimea, Ukraine). Maanta, tusaale ahaan, qaar ka mid ah Biofirm shisheeye (shirkadda «Antigenics Corporation») waxaa laga sameeyey unugyada burada kansarka ah bukaan bukaanka isla - wax tallaalka anti-kansarka ujeedooyin daaweynta (immunotherapy) horjeeda kansarka u gaar ah.

Sidaas darteed, waxaan kala saari karaa laba isbeddellada muhiimka ah ee daaweynta muxaafidka ah.

First.

Daawada si ay u gaaraan Jidka (etiology) ah, ama horumarinta hab cudurka (pathogenesis). Iyadoo la raacayo, tusaale ahaan, antibiotics, waxaa loo arkaa asal ahaan ku dhacaa sabab, baabbi'in wareer ah ee jirka ku jira, tus, in cudurada faafa. daroogada Antihypertensive sida caadiga ah u dhaqmaan on habab kala duwan (pathogenesis) ee hypertension.

Ogow, si kastaba ha ahaatee, gaar ahaan himiolecheniya. Xitaa cudurada raaga, xaaladaha badankooda, daawooyinka waxaa loo isticmaalaa gargaarka "xaalad degdeg ah". maalmood - Ie daroogada ee ugu fiican daawan doonaa isticmaalo.

Drugs-simaha sano iyo bilo, ma. Inkastoo, sida ay iyagu yidhaahdaan, oo dhan

cudurada raaga waxaa sababa doorashooyin hab nololeed oo liita, in uu yahay,

muddada-dheer iyo cudurrada ba'an iyo murugo - arrin fursad.

In daaweynta cudurada raaga ay isku dayayaan in cimrigiinnu ku tallaabo daroogada, tusaale ahaan, iyagoo isticmaalaya dhigaalka, ama by codsanaya "Nanocontainers la egyahay caaqil" kala duwan ama foomka sii dheerayn (tusaale ahaan, Bitsillin). Intaa waxaa dheer, inta badan ee cudurrada daawooyinka joojiyaan in ay ku shaqeeyaan, oo ay u leeyihiin in ay si joogto ah la beddelo, la beddelo "chemistry" ee jirka bukaanka ama genetics, oo sideeda oo antigenic of pathogene ah. Or, marka hore daawooyinka ma shaqeeyaan sabab u polymorphism hidde ama lagmamaarmaanna u (kala duwanaanta) ee u shaqeeyo bukaannada iyo wareer ah.

Taasi waa, in habkan daaweynta, daawooyinka loo isticmaalo qabashada ama saamayn oo keli ah qayb ka mid ah geeddi-socodka bahal ah, iyo sida ay ugu nooca ay gebi ahaanba shisheeye yihiin jidhka, tan iyo markii ay la soo saaray by hababka kiimikada.

Warku labaad.

Waxaa si cad u yahay shakhsiyaynta la arki karo, laakiin ku salaysan mabaadi'da la yaab leh. In homeopathy, at ugu wanaagsan, waxaa lagu qeexaa "nooca" bukaanka, liis kooban oo laysugu. Autohemotherapy (daaweynta uu dhiiggiisa) ma siin saamaynta ay ku doonay, ma aha oo kaliya in dhiigga si loogu daweeyo iyo ma aha oo gebi ahaanba cad, tusaale ahaan, Bulshda ee soo bandhigid sepsis dhiig bukaan-socodka u gaar ah. Oo waa Bulshda ahaantii hal dhinac la arki karo ee wax soo saarka iyo isticmaalka alaabta nafleyda ka iyaga u gaar ah ka dhigay, cudurka dib u habaynta, ie unugyada pathologically doorsoon. Xisaabinta, marka taas waxa laga sameeyaa, si kastaba ha ahaatee, oo ku saabsan wax ka qabashada difaaca jidhka. Laakiin jawaabi kartaa a counter-attack awood of habka difaaca jirka ku filan, dhammeysteen by cudurka, sida kansarka?

Muranka oggolyahay ee hargabka tallaalada, ka awood si ay u helaan talaalka ka AIDS iyo kansarka la xiriira iyadoo labada hidaha tirayn of wareer ah iyo hidaha xasilooni oo ka mid ah unugyada jidhka ee bukaanka (heterogeneity). Sida loo "qabsado" xaaladda kala duwan bahal beddelo pathogenesis, beddelo genetics ah habka cudurka iyo si degdeg ah beddelo genetics of sheyga bahal (ee loo yaqaan unugyada "pathomorphosis" iyo unugyada kansarka, HIV, heterogeneity ee AIDS)? Sida loo qabto waxa si degdeg ah la beddelo? Sida noocyada "qaboojiyay" daroogada in lagu daaweeyo aad u dhakhso-beddelo habka cudur ama wax si dhakhso ah hiddo modified?

Intaas waxaa sii dheer, sida waxaa la helay: hiddawadayaasha aadanaha ku jira oo dhan genomes yaqaan, oo ay ku jiraan protozoa pathogenic (wareer). (In this "eed" ee horumar). Sida loo joojiyo xasillooni darrada ah ee ay DNA u gaar ah ee kansarka iyo AIDS? Maxaa dhacaya haddii bilowga ah ee DNA cudurka oo keliya, ka dibna waa kala duwan yahay? Halkan failure ee wax soo saarka ee tallaalka cudurka kansarka iyo AIDS. Sida loo abuuro oo hubkiisa u ah noolaha (biobronyu) ee cudurada si gaar ah halis?

Waxaa jira saddexaad, isbeddel ah soo noqnoqda - alaabta nafleyda, ku salaysan bayotechnoolajiyadda - serum daaweynta, interferons, insulin, pirogenal (helay tiifowga), prodigiozan, bifidus, lacto-bacterins, iwm .. All of allotropic kuwan, oo la helay unugyada shisheeye iyo (micro) noolaha.

Tallaalka ma leh halkan ka qaban doonaan, sida caadiga ah waa, oo mooyee kuwa la xiriira ka hortagga.

Marka la isticmaalayo therapy (keydka dhiigga, diyaarinta protein ...), ayaa walaac weyn ee dhakhtarro waa dawo si fiican u ah oo sax ah "in line" la Kiimikada noole ah ee jirka, ma siin doono wax saameyn liddi ah, laakiin ka badan iyo daaweyn. Sidaa darteed, marka la isku duro, la isticmaalayo baarka kala duwan for "waafaqsan" la jirka bukaanka. daroogada Daaweyn laguugu beddelo sidoo kale ma bayoloji shaqsi.

Hadafka daaweynta kansarka iyo AIDS - in ay dilaan unugyada hiddo modified, ka dibna u ogolaan koritaanka barkadaha (of sprouts iyo qoysaskooda) ee unugyada caadiga ah ay.

Maanta Hidaha caadi unit isku day leedahay (autosomal) ee daaweynta ujeedooyin macmalay unugyada bukaanka qaba manipulations dhexe ee vitrum (technology -tube) isticmaalaya farsamooyin hidde injineernimada (iibsiga oo iskushaandheyn hiddo) isticmaalaya plasmids, fayrasyada, "fallaadhaha", iwm guulaha noocan oo kale ah waa suubban, iyo dhibaatooyinka iyo dhibaatooyinka genetics yaqaan iyo amaanaa.

Laba erayada ku saabsan genetics la ruxruxo. Waxaan aragnaa, waxaa jira dhibaato ee guud ahaan signalka aperiodic ka DNA caadiga ah, sababtoo ah E.Shredinger - DNA aperiodic. Ilaa hadda, in ay naga aqoon, oo aan la aasaasay matoor awood guud ahaan calaamadaha aperiodic ballaadhkiisuna wuxuu ahaa spectrum electromagnetic guud ahaan. therapy ruxruxo baabuurta si adag bayoloji ganacsiga, waxaa la "celcelis".

Taasi waa sidaas ka fog, in dawo jidka marto iyo dawooyinkooda, iyadoo la isticmaalayo, sida caadiga ah, walxaha shisheeye, noolaha, micro-organisms iyo genetics shisheeye - isku dayaya in ay caadi ka genetics iyo Kiimikada noole ka mid ah jirka ah ee qof gaar ah buka, in uu yahay - in ay isaga daaweeyo.

In daaweynta unugyada asliga ah loo isticmaalo qof kale ka ama unugyada adiga kuu gaar ah. Dhibaatada ugu weyn ee in daaweyn jiray unugyada asliga ah, in our opinion, waa taxriifin ee saamaynta ku daweynta ay sabab u tahay undecidability reer daqiiqado ah sida: 1. ma jiro wax fursad in kiisaska oo dhan waxay soosaaraan gaarsiinta ah lala beegsaday unugyada asliga galay la doonayo xubnaha, nudaha ama diirada; 2. ma jiro wax fursad si ay u siiyaan kasta oo ay gacanta degaaankaaga, unugyada asliga ah, 3. galay dhiigga unugyada asliga ah waa la kala sooc lahayn loo qaybiyey jidhka oo dhan; 4. ma jiraan wax damaanad dhaco unugyada asliga ah meesha ku haboon; 5. ma Saadaasha natiijada daaweynta sabab u qaybinta random unugyada asliga ah. 6. Saamaynta daweynta unugyada asliga ah ayaa lagu arkay oo keliya ayaa beerta ku dhow meel ay goobta; 7. saamayn systemic on jirka oo dhan ka soo saamaynta unugyada asliga si adag aan tijaabiyo sabab weli talaabo hoose ee unugyada asliga ah, iyo sababtoo ah qaladdaadka taranta: tirada degaaankaaga, unugyada (jirka) iyo tirada unugyada asliga ah ay maamusho.

Recently, aan sidoo kale ogaanaa arrimuhu ka selectivity cidhiidhsan garoomada ka abuuray by daroogada iska - ay milgadaa - si ay tallaabo toos ah on badan diirada.

In dhammaan kiisaska, si loo dawayn iyo dawo qof isku dayo in la isticmaalo sida saamaynta iyo daaweyn, kaas oo, ugu dambeyntii, caadi uu (bukaanka) oo dhan shaqsi Dheef (homeostasis) iyo / ama dhammaan ay genetics, taas oo macneheedu yahay soo laabtay gobolka ee caafimaadka.

Sayidka, muxaafid daweynta (pharmacological) Habka of tiriska shaqeeyo oo dhan (nidaamka oo dhan live) iyo hababka oo dhan, oo ay ku jiraan hidaha, - oo aan la furay iyo sida aan la isticmaalin.

Ugu dambayntiina, mid la soo dhaafay. xaqiiqooyinka Individual ee lama filaan ah (lama filaan ah) bukaanka daawo rajo la wareega 4 kansarka soo jeedin la mid ah: waxaa u sugnaadey noqosho ah in qofka caadiga ah ee dhammaan heerarka ururka: kelli, subcellular, gacanta, unugyada, xubin, iwm Taasi waa, inuu ku laabanayo caadiga ah, sharciyada "la isticmaalo" - waa hadafka ugu sareeya ee caafimaad iyo daaweynta. Haddaba maxaad u isticmaalin, waayo, daaweynta ee "caadi ah"?

Waxaa la fahamsan yahay in dib u soo kabashada iyo jidhka ku soo laabto si caadi ah, in qasac caafimaadka iyo in la sameeyo waa in si toos ah adiga oo isticmaaleya isticmaale,, macluumaad hooyo isla noolaha lagmamaarmaanna hidaha ee u gaar ah jirka unugyada caafimaadka qaba ay (degaaankaaga) sita macluumaadka buuxa noolaha isticmaalaya unugyada totipotent.

Looma baahna in la noqon dhakhtar in la ogaado in haddii qofka uu ku dhashay iyo ku noolaa in sano uu la lahayn wax calaamado la arki karo iyo dhibaatooyinka noqon kartaa muujinaysaa ay cudur hidde, waxay ka dhigan tahay default ah, kuwaas oo u badan tahay waa, nin genetics ahaa asal ahaan caadi. Sidaas daraaddeed, waad u isticmaali kartaa in unugyada jirka BIMF ujeeddo ah caafimaad iyo soo celinta caafimaadka qofka.

Si kastaba ha ahaatee, waayo cudurka of a state "caadi ah" unugyada degaaankaaga, waxaa loo isticmaali karaa sida horumarintooda (marka la akhrin) oo hiddawadayaasha (hab qaali ah, sirgaxan, sirgaxan loogu isticmaalo socodka hiddawadayaasha) iyo "Baadhista hiddawadayaasha for calamado ah cudurada guud" - borotiinada histone (la heli karo, laakiin aan ku habka yar sax ah ee qiimaynta gobolka ee hiddawadayaasha ah, gaar ahaan - in ay horumarinta firfircoon oo ka mid ah Ruush -. qoraaga Paponov Vladimir D. et al, xarunta Hidaha Research Medical wanan, Moscow) ..

Goolal - horumariyo mabaadi'da iyo aasaaskii sayniska ee dawada shakhsi iyo daaweynta ku salaysan ahayn mabaadi'da dawooyin kiimiko (hababka) - ayaa la dhigay sida mudnaanta ee qaybaha muhiimka ah ee barnaamijka ee tignoolojiga Development of Russia muddada 2007 - 2011, ay qaateen Dowladda Ruushka. ujeeddooyinka Kuwaas waxaa lagu gaari noo by.

Si aad u taariikhda, ujeedooyin ee hufan (by abuuray of opinion) iyo daaweynta ugu ammaan ah - taasoo keentay dawooyinka iyo bayotechnoolajiyadda therapy dunida ee isticmaalaa ugu guuleysan karo ee "individualization" xulashada iyo wax soo saarka ee daawooyinka.

Indeed, waxaa weeye hadhuudh runta ah ee xaqiiqda ah in ee soo saaridda daroogada saarayaasha, liiska hoos ku qoran, waayo, aawadiis of "universal" shaqsinimo, individualization, biotechnological farsamooyin ay ku haraan antigenic group, gaar guryaha daroogada of noolaha walxaha uu ka samaysan, kuwaas oo la mid ah daroogada, oon keddibna (ka tagin) ay antigenicity , allogeneic (foreignness noolaha). Sidaasay u lifaaqan "caalamiyeen" si aad u dalbato in "dhammaan" daroogada sida.

Habkan in soo saaridda ee medicaments waa mid aad u badan sida isticmaalka unugyada asliga ah ee biotherapy, iyo "arbushaad" dareenka ay heterogeneity (shisheeye), sidaas darteedna - tilmaamaha "universal" loo isticmaalo.

Sidaas darteed, soo diyaarinta adag Jarmal «Cidhibta» iyo / ama Talyaani «Oti» (Officine Terapie Cusub) ku jira (ama ku talo jiraan in ay isticmaalaan)

homeo (la mid ah) + + bedelka Organotropona (bedelay) maaddooyinka.

(Eeg., Siday u kala horreeyaan, tusaale ahaan, Catalog oo ka mid ah diyaarinta shirkadda Jarmal "Biologishe Haylmittel ciribta GmbH" General Medicine 2011-2012, JSC "leporis Alfa», 2011. www.heel.com) (Quick Reference "Compendium" daawooyinka walaac Oti www. otiomeopatici.com).

Iyo, ilaa ugu dambeyntii, daawooyinka ka kooban walxo pharmacologically firfircoon - iyo-organic bioregulators cell unugyada-gaar ah (peptides, iwm) Of the xubnaha iyo unugyada (wadnaha, maskaxda, qanjirka pineal, xiidmaha yar-yar, xiidmaha waaweyn, erythrocytes, beerka, ugxan kala duwan, dheecaanka qanjidhada, qanjirka caanaha, unugyada muruqa, kalyaha, dhuuxa lafta, beeryarada, pituitary, sambabada iyo sambabbada, caloosha, prostate, beeryarada, thymus dhalinyaro ah, thyroid, ilmo galeenka, xiniinyaha, unugyada embriyaha uurjiifka), soo saaray maanta «vitOrgan» shirkadda ( Germany).

Bixiya daawooyinkan, «vitOrgan» dhawaaqday intii suurto gal individualization saxda ah, shaqsinimo gaadhista daroogada. daroogada waxay ka kooban yihiin ka difaan (weli) xoolaha kiciyey jawi nadiif ah iyo quudintooda nadiifiye.

Maanta, maskaxda oo ka Russia si cad u wareejiyay dhinaca jinsiyadda sida cunto iyo daawo. All waa yar tahay in ay sii, waayo, isticmaalka iyo adeegsiga Chemical Farmashiga ee daroogada. Dadka kala fur wejigaaga ee dabiiciga ah, oo doorbiday dawooyinka dabiiciga ah iyo cunto, sida ka soo horjeeda kiimikaad dhexsameeysmo jirka iyo ahayn.

Fiirsaneysa inay kor ku xusan oo dhan, waa in la sheegay in hab ee dawooyinka caalamiga ah iyo bayotechnoolajiyadda for shaqsinimo, individualization daawooyinka noolaha naftooda iyo individualization (bio) teknoolajiyada ay wax soo saarka.

A waqti yar, iyo "gaari doonaa oo dhan" waxa daawooyinka waa in ay helaan iyo iyaga ula dhaqmaan by farsamooyinka caafimaadka noolaha-shaqsi (BIMF).

Waayo, ka dibna sii joogi doonaa mudnaanta of technology this?

Hababka isticmaalka

teknoolajiyada shaqsi bio-caafimaad (BIMF)

si loogu daweeyo ama shakhsiyaynta daroogada dawooyinka caadiga ah,

oo aan bixinta ogaada-sida.

bixiyay dhowr nool ay ku jirto nuclei cell caafimaad, waayo, qasti kasta oo jidhka ah daaweynta cudurka, jirka ka mid ah bukaanka ka.

Comment.

Saaridda ka unugyada shaqeeyo lagu qaado invasive (iyada oo la qalay, dalool) iyo (Majar) noninvasive habka (tusaale ahaan, galaas ama qorid on xoqo gacanta). In jirka wax kasta oo buka, haddii aanay cudur dhaxlay hidde 100% guul darro oo dhan unugyada, mar walba diyaar u yihiin inay caafimaad ah, la genetics caafimaad degaaankaaga (jirka) unugyada. Haddii loo baahdo, laga soo unugyada mid ka mid ah u shaqeeyo, oo ay ku jiraan arkidda laga soo qaaday unugyada ama xubnaha, sida in la helo hawl. Waayo, ujeedooyinka BIMF bixiyay oo loo isticmaalo unugyada caadiga ah ay ku jiraan xuduntii ah (eukaryotic) iyo lifaqaya diploid ah (buuxa, double) set of koromosoomyada, in uu yahay, hiddawadayaasha dhameystiran - unugyada totipotent iman kara. Sida by genetics casriga ah ayaa sheegay, waa unugyada totipotent ku jira macluumaad dhamaystiran (oo ay ku jiraan hidaha) ee jirka ka kaas oo ay qabsadeen, ka unugyada kara totipotent awood u koraya shaqeeyo oo dhan (Dolly idaha).

Help.

Si adag hadlayay - jirka (degaaankaaga) unugyada, unugyada ay leeyihiin, aan maanta loo yaqaan totipotent, oo kala. totipotent A loo yaqaan unugyada jirridda ee embriyaha oo kaliya. Xitaa gacanta laaluusheen pluripotent stem (IPS) waxaa lagu magacaabaa pluripotent ...

Muhiim waa xaqiiqda ah in degaaankaaga ku diploid (jirka) unugyada qaado totipotency buuxda iman kara.

Iyadoo unugyada soo saaro jidka (technology) oo gaar ah ayaa la musuq maasuqay iyo tallaabooyinka ay sabab u tahay taas oo qaawan, go'doon iyo saaray oo dhan ka kooban yahay mid ka mid ah unugyadan, ama dhamaan macluumaadka noolaha ka unugyadan. Xaaladdan oo kale, haddii loo baahdo, nooca gacanta (siyaada tissue) unugyada waxaa laga yaabaa in optional ama mid dhexdhexaad ama ku kaydsan, ama modified. Markaas waxyaabaha uu gacanta oo dhan, ama macluumaad ku saabsan noolaha ku jira gacanta dhufasho (tarmaa) hab gaar ah oo dhexdhexaad ah oo gaar ah (carrier).

Comment.

Tani waa guul weyn ka BIMF. Marka unugyada daaweynta xilligan la joogo waxaa loo isticmaalaa sida farsamooyinka caadiga ah oo caan ah iyo technology iyo sidoo kale gaar ah (cilmi), mideysan hal wareeg farsamada. Unugyada iyo / ama waxyaabaha ay la kulmaan, ka mid ah amar, technology kiimikada Sol-gel ah, micromanipulation, joogo ama ku kora shaybaarka saamayn dhaqamada cell vacuum, heerkulka, saamayn, iyadoo la isticmaalayo qalab habeysan la micro-nanolayers iyo daloolada ... gaar ah loogu dhaqmo iyaga isku darayo dhammaan heerarka kala duwan ee technology ee.

kiis gaar ah iyo nooca adkeyneyna macluumaad noolaha maanta waa, tusaale ahaan, technology PCR (polymerase Reaction Chain), ayaa ku tilmaamay aragti ahaan in 1971 iyo soo jeedinta wax ku ool ah ee 1983.

Iyada oo PCR, sida la og yahay, waxay dhacdaa multiplexing (dhufashada, isu-dhufasho, koobiyeynta soo noqnoqda, Faahfaahin) macluumaadka noolaha oo ah qaab DNA (jajabkii ay).

Duulimaadki waxay ka kooban tarmin ku dhex jira wax noolaha, macluumaad ku saabsan dhismaha unugyada caafimaad qaba, in uu yahay - on caafimaadka gacanta - waxaa dawadu jidhka ee bukaan-socodka qofka, taas oo uu unugyada degaaankaaga shakhsi caafimaad markii hore ka noqday.

Comment.

dhexdhexaad A oo ka kooban macluumaad ah bayoloji-shakhsi, marka ay maamulaan in a qeybaha balan qaadayo iyo guskiisa galay dhammaan unugyada degaaankaaga. Waxaa doonaa sidaas loo soo bandhigin mar oo dhan unugyada degaaankaaga. Xusuuso: macluumaadka dheeraadka ah bayoloji-shakhsi ah ee taageerada bixiya ay isku dhufashada (dhufashada). Tusaale ahaan, macluumaadka noolaha waxaa laga soo unugyada 10 laga yaabaa in lagu multiplexed in malaayiin ama balaayiin koobi. Sayidka, ee ficil iyo this warbixin doono hayeyna by tallaabo malaayiin iyo bilyanno unugyo!

Sidaas darteed, jirka bukaanka helo in xad-dhaaf ah oo u gaar ah (si adag shaqsi bayoloji!) Macluumaad ku saabsan iska caadi ah ee caafimaadka. macluumaadka caafimaadka dheeraadka ah ee jirkaaga si hubaal ah u noqon, (notes) dib macluumaadka bahal ah iyo geedi socodka, ie - normalizes iyo daaweeyo bukaanka. macluumaadka caafimaadka noolaha xad-dhaaf gaar ah u kordhin doonaa si weyn kor caadiga ah ee jeer iska caabin ah jirka ee saameynta kasta.

Faa'iidada iyo muuqaalada BIMF

(Technology caafimaad Bio-shaqsi).

BIMF waa mid ka mid ah oo isku daraa laga yaabaa in dhammaan noocyada kala duwan ee maanta sare teknoolajiyada - nano-, gaasta cryogenic, vacuum, unugyada, Sol-gel, Pharma, copper, mikroinstrumentalnye - kaliya la xiriira codsiga of live nidaamka iyo waqti isku mid ah waxaa ku jira mideynaya ah - the "element shanaad". technology isticmaalay iyo plasma, qalabka vacuum-heerkulka sare ee processing iyo wax soo saarka oo ah alaabta iyo galaasyada shaybaarka.

technology wuxuu kuu ogol yahay in aad ka bogsato (bogsiiyaan) sida jirka oo dhan, iyo xubnaha ay gooni ah iyo unugyada - isbedel ku haboon ee technology-socodka.

Sharaxaada.

Habka BIMF si guul leh horumariyo karaa teknoolajiyada hadda jira ayaa maanta sii kordhaya xubnaha autologous iyo unugyada.

Habka BIMF sidoo kale waxay suuro gelineysaa in aad u isticmaali loogu tala galay ujeedooyinka joojinta ama revertirovaniya (beddeli) isbedel da'da la xiriira si degdeg ah oo dhan u shaqeeyo oo dhan.

Habka BIMF u ogolaanaya si gaar ah shakhsiyeeyo diyaarinta dawooyinka caadiga ah, "qabsado, la beddelo oo ay qaab-dhismeedka" hoos Kiimikada noole ah ee u shaqeeyo ama unugyada bukaanka iyo unugyada, kuna waari dhexdeeda conformation ka da'ayeen ee u taagoo daroogada ma bedeli doonto formula taaban karo. (Ha ku xadgudbayn xuquuqda saarayaasha daroogada). Habeeyay si buuxda u diyaarinta dawooyinka BIMF ku haboon yahay jirka bukaanka, oo sidaas daraaddeed kordhiyo doonaa saamaynta ay ku daweyn iyo waqti isku mid ah la yaraynayo ay waxyeello ka soo gaartey ama sun, isagoo si gaar ah konformirovannym.

Sharaxaada.

BIMF isticmaalka Tani waxay noqon doontaa ah "dahabka" bartamihii - tanaasulka dhexeeya saarayaasha daroogada - farmfirm (farmbiznesa) on gacanta ku hal, iyo BIMF - Gaarna shakhsi "bezhimicheskoy" technology daroogada, ayaa dhanka kale, taas oo daroogada ah ka igredientov u shaqeeyo gaar ah ka dhigay. Ka dib oo dhan, technology muhiimad tiraa BIMF isticmaalaan in daaweyn jiray Farmashiiste kiimikada, ie ka dhigayaa warshadaha kiimikada aan loo baahnayn ee dawooyinka sida. Si kastaba ha ahaatee, sida war qoraal ah oo geesi ah, oo ma aad samayn karaa iyadoo la isticmaalayo BIMF iyo kiimikada diyaarinta caadiga ah lagu daro, si kor loogu qaado saamaynta ku daweynta ee wadajirka ah.

Waxaa la og yahay in, tusaale ahaan, vitamin C caanka (ascorbic acid), isagoo formula isla taaban karo sida Britain ayaa waxay leedahay 28 gaadmada ah aan ollogga (isomers), oo kaliya mid ka mid ah taas oo uu leeyahay hawl noolaha ee aadanuhu. orientation da'ayeen inta badan waa sabab muhiim ah waxtardarradoodu ficilka daroogada. Oo sidii xaqiijin ah, waayo, kaasu waa wax isbedel ah oo conformation ka da'ayeen of protein waa sababta cudurada prion (encephalopathy spongiform cudurka = = waalan lo'da, scrapie , iwm ..), Yaa maanta ma oga - sida loo daweeyo. (Prions - noocyada protein).

All sameeyey taariikhda daawooyinka waxay leeyihiin qaab da'ayeen, oo sidaas daraaddeed awood spatially konformirovatsya.

Waayo, habka BIMF daawooyinka aan muhiim dhismeedka da'ayeen aasaasiga ah, waayo, kaasu konformirovana doonaa iyadoo la raacayo shaqsi ee Kiimikada noole ah ee u shaqeeyo (ama unugyada) ee bukaanka ah.

Habka BIMF waa mid gaar ah in ay fulinta iska indho sababaha (etiology) cudurka iyo hab ay cudurka (pathogenesis), oo ay si fudud ku tacaluqda (marka laga reebo cudurada dhaxlay) waa.

Habka sidoo kale waxay suuro gelineysaa in lagu daaweeyo prion iyo cad qaar ka mid ah cudurada hidde dhaxlay, iyo hadii kan danbe - haddii waalidku nool yihiin iyo / ama probands (walaalahaa wiilal ama gabdho) ee bukaanka ah.

In habka of adkeyneyna BIMF la hoos gelin doonaa macluumaadka noolaha on hababka oo dhan iyo waxa ku jira oo dhan oo ah unug - yaqaan iyo aan la aqoon in ay taariikhda.

BIMF u ogolaanaya codsanaya macluumaad kala duwan yihiin waqti ka bukaan isku si guul leh ku bogsiiyaan, inkastoo ay kala duwanaan hidaha ee wareer ama unugyada (tissue) ee u shaqeeyo.

BIMF kuu ogolaanayaa inaad la unugyada xubnaha 'dhibaatada iyo nudaha ka shaqeeyaan, oo labada si gooni gooni ah iyo si wada jir mar - sida ay dhacdo in jidhka. Habka waxa uu ka dhigayaa suurto gal ah in ay iska indha, in uu yahay, in aan la taaban dhibaatada waxa loogu yeero ee Hayflick (yareysey tirada maytosis 50 unugyada degaaankaaga, telomeres dhibaatooyinka telomerase), sida in la helo natiijada la doonayo in technology-socodka waxaa loo isticmaali karaa unugyada BIMF kaliya jiilka "dhallinyarada" - ie unugyada ka "marka hore, hore" mitoses.

In BIMF aan aan la isticmaalin: hidda Engineering (hababka isku shaandheyn iyo kala iibsiga hiddo), cloning noolaha, shucaaca iyo technology kale deegaanka waxyeello ama wasakh. qiiqa Biological deegaanka lagu jiro BIMF dhigma oo kaliya in ay hawada ka gacma saabuun ama jidhka.

Hababka isticmaalka

teknoolajiyada shaqsi bio-caafimaad (BIMF)

loogu tala galay ujeedooyinka joojinta gaboobaya (anti-gabowga), ma uusan carabaabin ogaada-sida.

technology kooban waa tan: ka ah unugyada jirka dhalinyarada waxaa soo bixiyay. Haddii jir ah u shaqeeyo, ay unugyada, ka dib markii ka fiirsato, kaalinta galay shaybaarka unugyada dhaqamada giisa halkaas oo ay ku tarmeen iyo dib u soo kacday. Laga soo qaaday ama soo minguuriyey unugyada yar yar oo dhan bixiyay macluumaad noolaha oo waxaa loo wareejiyey dhexdhexaad ah halkaas ku tarmaan (dhufasho). Markaas warbaahinta la this macluumaad "dhallinyarada" noolaha waxaa soo bandhigay in ka badan ee jirka ku jira oo guskiisa galay dhammaan unugyada ay. Sidaas darteed, jirka helo in xad-dhaaf ah oo isaga u gaar ah macluumaad noolaha "dhallinyarada", taasoo keeni doonta in ugu yaraan joojin da 'ah ama isbedel weyn. (Bixiso sharaxaad faahfaahsan oo dheeraad ah.)

Sidaas darteed, marka loo isticmaalo in u shaqeeyo oo dhan BIMF gaari adag shaqsi (shakhsi, shakhsi):

1. daawo;

2. The anti-gabowga (isbedel) ama qamaar da'da noolaha;

3. shakhsiyaynta dawayn lahaa dawooyinka farmasiga caadiga ah;

4. biobronya: hortagga guud ee shakhsiga ah (Faahfaahin in times of dhammaan guryaha difaaca nafleyda ee u shaqeeyo).

In codsiga ah ee teknoolajiyada kuwaas oo dhan ka mid ah iyo qof la mid ah, waxaan u gee qofka isla, laakiin waa in qaab cusub! Isla mar ahaantaana, isagu xaq buu isu weli, waa in - uu sii ahaan doono shaqsi la mid ah, shakhsiyadda isla, shaqsi.

Sidoo kale, mashruuca BIMF loo qaybin karaa sub-4 ka mid ah, kuwaas oo loo hayn doonaa saldhig uniform - BIMF. Iyo, dabcan, oo dhan afar meelood loo qaadi kari waayeen xarunta hal BIMF.

Habka Isticmaalka (Habka)

teknoolajiyada shaqsi bio-caafimaad (BIMF)

loogu tala galay ujeedooyinka joojinta gaboobaya (anti-gabowga), ma uusan carabaabin ogaada-sida.

technology kooban waa tan: ka ah unugyada jirka dhalinyarada waxaa soo bixiyay. Haddii shaqeeyo jir ah, unugyada ay, ka dib markii ka fiirsato, kaalinta galay a dhaqamada cell shaybaarka giisa halkaas oo ay tarmaan iyo dib u soo kacday. Laga soo qaaday ama soo minguuriyey unugyada yar yar oo dhan bixiyay macluumaad noolaha oo waxaa loo wareejiyey dhexdhexaad ah halkaas ku tarmaan (dhufasho). Markaas, side of this macluumaad "dhallinyarada" noolaha waxaa soo bandhigay in ka badan ee ah dadka da'da ah (jirka), jidhka iyo guskiisa galay unugyada oo dhan. Sidaas darteed, jirka helo in xad-dhaaf ah oo isaga u gaar ah macluumaad noolaha "dhallinyarada", taasoo keeni doonta in ugu yaraan joojin da 'ah ama isbedel weyn.

Comment.

Saaridda ka unugyada shaqeeyo lagu qaado invasive (iyada oo la qalay, dalool) iyo (Majar) noninvasive habka (tusaale ahaan, galaas ama qorid on xoqo gacanta). Lessons unugyada yar ama unugyo yar yar dheefay waxaa lagu qori karaa Wixii rahmaad ah ee Cryobank ilaa ay waxaa loo isticmaalaa. unugyada cryo-kaydinta iyaga bixisaa daryeel, taas oo ah, ku dhowaad - agelessness. Haddii loo baahdo, jidhka baxey unugyada kasta, oo ay ku jiraan arkidda ka unugyo ama xubnaha, sida helitaanka-waqtiga dhabta ah qaaday haddii loo baahdo in arkidda ku xiga ama degaanka "nooleynaya" xubnaha ama unugyada. Waayo, ujeedooyinka BIMF bixiyay oo loo isticmaalo unugyada caadiga ah ay ku jiraan xuduntii ah (eukaryotic) iyo lifaqaya diploid ah (buuxa, double) set of koromosoomyada, in uu yahay, hiddawadayaasha dhameystiran - unugyada totipotent. Sida by genetics casriga ah ayaa sheegay, waa unugyada totipotent ku jira macluumaad dhamaystiran (oo ay ku jiraan hidaha) ee jirka ka kaas oo ay qabsadeen, ka unugyada totipotent ay awoodaan si ay u horumariyaan u shaqeeyo oo dhan. Taasi waa, dhammaan baahida runta ah ee u shaqeeyo guud ahaan, sida nidaamka nool waxaa lagu bixiyaa ama lagu bixin karo potencies (awoodaha) unugyada totipotent. Taasi waa sababta unugyada totipotent iman kara waxaa loo isticmaalaa in BIMF.

Iyadoo unugyada yar ama dib u soo kacday ee jidka gaar ah (technology) ayaa maasuqay iyo tallaabooyinka ay sabab u tahay taas oo qaawan, go'doon iyo saaray oo dhan ka kooban yahay mid ka mid ah unugyadan, ama dhamaan macluumaadka noolaha ka unugyadan. Xaaladdan oo kale, haddii loo baahdo, nooca gacanta (siyaada tissue) unugyada waxaa laga yaabaa in optional ama mid dhexdhexaad ama ku kaydsan, ama modified. Markaas waxyaabaha uu gacanta oo dhan, ama macluumaad ku saabsan noolaha ku jira gacanta dhufasho (tarmaa) hab gaar ah oo dhexdhexaad ah oo gaar ah (carrier).

Comment.

Tani waa weyn oo guul ku BIMF. Marka unugyada ayaa la daweeyey xilligan la joogo iyo sida loo isticmaalo sida tijaabada ah ee farsamooyinka loo yaqaan iyo technology, iyo sidoo kale gaar ah (cilmi), mideysan hal wareeg farsamada. Unugyada iyo / ama waxyaabaha ay la kulmaan, si gaar ah ma, technology kiimikada Sol-gel ah, micromanipulation, joogo iyo koraan dhaqamada cell shaybaarka, saamaynta vacuum, heerkulka, saamayn, iyadoo la isticmaalayo qalab habeysan la micro-nanolayers iyo daloolada ... Waxay ku xiran qaarkood waa isku darayo dhammaan heerarka kala duwan ee technology ee.

kiis gaar ah iyo nooca adkeyneyna macluumaad noolaha maanta waa, tusaale ahaan, technology PCR (polymerase Reaction Chain), ayaa ku tilmaamay aragti ahaan in 1971 iyo soo jeedinta wax ku ool ah ee 1983.

Iyada oo PCR, sida la og yahay, waxay dhacdaa multiplexing (dhufashada, isu-dhufasho, koobiyeynta soo noqnoqda, Faahfaahin) macluumaadka noolaha oo ah qaab DNA (jajabkii ay).

Duulimaadki waxay ka kooban tarmin ku dhex jira noolaha, macluumaad dhismaha wax ku saabsan a cell dhalinyaro ah oo caafimaad qaba, in la - on waxyaabaha gacanta u dhiganta gacanta ee dhalinyarada - waxaa dawadu jidhka ee bukaanka shaqsi (macmiilka), taas oo uu unugyada degaaankaaga shakhsi caafimaad markii hore ka noqday.

Comment.

Erayga "dhalinyarada cell" waxaa loola jeedaa xaaladda iyo waxyaabaha ka mid ah unugyada baahisey in ay dhalinyarada, taas oo ah - kii ugu horreeyey ee hore maytosis. dhexdhexaad A oo ka kooban macluumaad ah bayoloji-shakhsi, marka ay maamulaan in a qeybaha balan qaadayo iyo guskiisa galay dhammaan unugyada degaaankaaga. Waxaa doonaa sidaas loo soo bandhigin mar oo dhan unugyada degaaankaaga. Xusuuso: macluumaadka dheeraadka ah bayoloji-shakhsi ah ee taageerada bixiya ay isku dhufashada (dhufashada). Tusaale ahaan, macluumaadka noolaha waxaa soo bixiyay 10 unugyada yar yar (ama isbedel weyn) waxaa la multiplexed kartaa in malaayiin oo balaayiin koobi. Sayidka, ee ficil iyo this warbixin doono hayeyna by tallaabo malaayiin iyo bilyanno unugyo!

Noqday caafimaad degaaankaaga, unugyada dammaanadda ay adagtahay of shil iibsiga cudurka in noolaynta jidhka, fulinta ee ujeedada joogsan BIMF gabowga ama isbedel.

Sidaas darteed, jirka ah ee bukaanka waxay heli doonaan in ka badan u gaar ah Macluumaad ku saabsan gobolka oo dhallinyaro ah (shakhsi si adag bayoloji!) - state ee unugyada yaryar. macluumaadka dhalinyarada iyo xad-dhaaf ah ee jirka ku jira waa la hubaa in ay joojiyaan iyo laaban (notes) beddeli isbedel iyo geedi socodka da'da la xiriira, oo la - istaago ama rejuvenates bukaanka gaboobaya.

Faa'iidada iyo muuqaalada BIMF

(Technology caafimaad Bio-shaqsi)

si ay u joojiyaan gabowga ama isbedel.

BIMF waa mid ka mid ah oo isku daraa laga yaabaa in dhammaan noocyada kala duwan ee maanta sare teknoolajiyada - nano-, gaasta cryogenic, vacuum, unugyada, Sol-gel, Pharma, copper, mikroinstrumentalnye - kaliya la xiriira codsiga of live nidaamka iyo waqti isku mid ah waxaa ku jira mideynaya ah - the "element shanaad". technology isticmaalay iyo plasma, qalabka vacuum-heerkulka sare ee processing iyo wax soo saarka oo ah alaabta iyo galaasyada shaybaarka.

technology wuxuu kuu ogol yahay in ay u nooleynaya jirka oo dhan, iyo xubnaha ay gooni ah iyo unugyada - isbedel ku haboon ee technology-socodka.

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