Reactions Leukemoid carruurta: nooc ah (noocyada), sababaha, daaweynta isku geynta cudurka. reactions Leukemoid iyo leukemia: kala duwanaanshaha

reaction Leukemoid - badala hematopoiesis, la mid ah sawir dhiig leukemia iyo burooyin kale ee nidaamka hematopoietic ah. Waa in la ogaadaa in cayimayo ee saamaynta waa ay orientation firfircoon iyo la'aanta guurka ee kansarka. Waxyeellada waxaa la keeni kara intiisa kala duwan noocyada, burooyinka, cudurada, kansarka maskaxda xadka-.

Farsamo ee horumarka kala duwan leh noocyada kala duwan ee falcelin: mararka qaarkood waa wax soo saarka ee xubno unugyada dhiigga aan weli qaan gaadhin, in dadka kale - wax soo saarka kor u kacay unugyada dhiigga ama xanibaad unugyada wax soo saarka ee unugyada ah, ama joogitaanka dhowr farsamooyinka isku mar.

Maxay noqon karaan ilaha cudurka?

Waxaa jira qodobo badan oo ku dhici kara falgalo leukemoid sabab. Sababaha ay horumarka waa:

• saamayn of ionizing shucaaca,
• qaaxada;
• sepsis;
• geeddi socodka carow ah;
• dabadhiig qaba;
• cudurka Hodgkin;
• trauma cranial;
• lama filaan ah;
• pneumonia lobar;
• erysipelas;
• diphtheria,
• qandho iyo casaan,
• Dystrophy beerku;
• therapy corticoid;
• carbon monoxide sumowga.

cudurka kala duwan

The noocyada soo socda ee reactions leukemoid:

• reaction Myeloid.
• Lymphocytic.
• Psevdoblastnye.

Ha ka fikiro si aynu mid kasta oo iyaga ka mid ah si faahfaahsan.

myeloid

By noocan ah falcelin ka mid ah sida nuutrofilkaagu, eosinophil iyo promyelocytic. saamaynta Leukemoid la mid yihiin kuwa leukemia myeloid chronic, Ulasocto sarkhaan iyo cudurada daran. leukocytosis Active asal ahaan mar walba geedi socod murugsan Ulasocto joogitaanka sepsis, iyo Axdigu bararka iyo heerkulka jidhka kordhay.

Gaadhista ka badan eosinophils in dhiigga u muuqdaan in ay dhacaan marka wacyi in dulin iyo daroogada, diathesis xasaasiyad, dhif - at cudurada oncological (cudurka Hodgkin iyo lymphosarcoma). Waxyeellada waxaa leukemoid u baahan tahay baadhitaan dhamaystiran cudurada cinwaanka nidaamka wareegga dhiigga, iyo Gooryaanka.

unugyada Tixgelinta sida eritremii. arrimaha polycythemia - inta badan waa hoos u dhac in nno sambabada Oxygen (oxygen) dhiigga, burooyinka kelyaha, iyo cudurada wadnaha lagu dhasho. xaaladda Tani waxay u baahan computer ah iyo ultrasound.

Mielemiya la mid ah erythroleukemia ba'an, taas oo ka duwan oo kaliya in la'aanta ah ee qaraxa erythrocytes dhuuxa lafta iyo dhiig. Inta badan waxaa suurtagal ah in la ogaado in metastases cudur lafaha.

lymphocytic

reactions Kuwan waxaa lagu gartaa koror weyn oo tirada guud ee limfosaytis in dhiig durugsan, taas oo inta badan mas'uul ka yahay in la kordhiyo beerka, mergiga iyo beeryarada.

Si noocan ah waxaa iska leh mononucleosis, faafa lymphocytosis, reactions leukemoid monocyte-qorayo in carruurta la jeermiska iyo Fayraska, iyo cudurada dulinka iyo eosinophilia dhiig oo sareeya (tus, helminthiasis).

reactions Lymphocytic dhacaan:

• cudurada viral (busbuska, rubella, mumps, cudurka adenovirus, jadeecada, mononucleosis faafa);
• cudurada dulinka (rikketsiozah, toxoplasmosis, chlamydia);
• cudurrada bakteeriyada (syphilis, pertussis, qaaxada);
• mycoses kala duwan;
• shalalka (cudur serum, lupus erythematosus oo nidaamsan).

nooca Lymphocytic badan ee macroglobulinemia Waldenstrom, caabuq, sarcoidosis. Dhammaan oo ka mid ah cudurrada kor ku xusan waxaa lagu daaweeyaa si aad u daran oo lagu wareeri bukaanka ka badan sanad karo.

Psevdoblastnye

Dareen-celinta noocan oo kale ah waxaa leukemoid haddii bukaanku uu bilaabayo oo kaliya in ay kasoo baxdo Agranulocytosis difaaca, sababta oo waxa keeni kara soo dhaweynta ee sulfonamides, "aminopyrine," "butadiene" iyo daroogooyinka kale.

Waayo group saamayn sida lagu gartaa joogitaanka dhiigga iyo dhuuxa lafta tirada durugsan badan qaybaha gacanta la core ah oo dhqaalaha, iyo nucleoli buluug hal, khafiif ah, oo aan lahayn cytoplasm a granular.

Si ka duwan qaraxa caadiga erythrocytes shabakadaha waxay leeyihiin fiiloyin chromatin jilicsan oo wuxuu qiyaasay gaar ah. blastosis aan joogto ahayn iyo baaba 'aan chemotherapy iyo saameynta leukemoid la xiriira waxaa laga helaa carruurta dhasha xanuunada koromosoomyada genetic (tusaale ahaan, Down syndrome).

noocyada falcelin Leukemoid oo lagu kor ku soo bandhigay, taas oo loo sameeyay ku saabsan asalka ah ee cudurada kasta, sida caadiga ah ma keenaan dhibaatooyin khatar ah. Mararka qaarkood si weyn u muuqday Torombositobiiniya laga yaabaa in si khaldan loo arkaa mid ka mid ah calaamadaha of leukemia ba'an. ogaanshaha immunoblastic lymphadenites muhiimadda badan yahay ammaanka qaab-dhismeedka dabiiciga ah ee Guntin lymph, iyo sidoo kale in si sax ah loo ogaado line ee kiishashka.

reactions Leukemoid iyo leukemia: kala duwanaanshaha

Waxaa jira qaar ka mid ah kala duwanaanshaha u dhexeeya saamayn sida iyo leukemia, kuwaas oo:

1. Marka falcelinta isbedel leukemoid offline dhuuxa lafta degdeg ah, waa metamielotsitarnym oo la ogaado kororka foomamka qaraxa leukaemia. Marka saamaynta leukemoid badbaadiyey jeermiga erythroid, waxaa jira a ratio leykoeritroblasticheskoe caadi ah - 3: 1 iyo 4: 1.
2. Ma daliilka arki karo of anaplasia la ifafaale leukemoid sida ay dhacdo in leukemia marka ay jirto ferjiga ka mid ah protoplasm oo logu talagalay xuduntii.
3. In muuqashadii ugu horeysay, ee dhiiga durugsan ayaa la kordhiyo tirada buuxda oo boqolkiiba kordhay neutrophils baaluq in content leukemia hoos neutrophils baaluq dhacdaa kororka xad-dhaafka ah ee dhalinyarada ah, foomamka aan weli qaan gaadhin.
4. Marka falcelinta leukemoid inta badan lagu arkay granularity sun ah neutrophils.
5. Marka leukocytes waxbarasho cytochemical in leukemia hoos u dhac ama maqnaanshaha of phosphatase ah xumadoodu, at reactions leukemoid - waxqabadka siyaaday.
6. Inta lagu jiro sii daridda ah ee horseed dhibaatada qaraxa leukemia myeloid chronic waa eosinophilic, ururka basophilic la offline reactions leukemoid.
7. Marka leukemia myeloid badanaa thrombocytosis sare, iyadoo falcelin leukemoid dhiig xinjirowga tirin gudahood kala duwan ee caadiga ah.
8. In marxaladaha hore ee leukemia myeloid chronic heli a beeryarada cufan weyn reactions leukemoid mararka qaar dhacaya splenomegaly, laakiin jidhku waa jilicsan iyo ma Gaadho size aad u weyn.
9. Marka falcelinta leukemoid hanaanka neoplastic ogaado in unugyada kansarka dhuuxa lafaha.

reactions Leukemoid carruurta: geynta ogaanshaha

doorka muhiimka ah ee lagu ogaado xanuunka la siiyo histopathology oo sheegaya waxyaabaha biopsy. Laakiin si looga fogaado khaladaadka hagaajin, pathologist waa in ay ururiyaan macluumaad sax ah oo ku saabsan bukaan-socodka, isaga siin jihada ee imtixaanada kala duwan iyo in uu magacaabo daaweyn cytostatic, taasoo meesha ka saaraysa dhan cawaaqibka lymphadenitis. Haddii waxaas oo dhan aan loo samayn, cudurka si sax ah lagu sameeyo, oo sidaas daraaddeed si ay ula qabsadaan cudurka uu noqon doono mid aad u adag. Ka dib oo dhan, cudurkan waa mid aad u halis ah. Mararka qaarkood, waayo gabagabeeyo faahfaahinta loo baahan yahay in la sameeyo biopsy celiyaan.

muhiimadda badan soo ogaanshaha muuqaalka smear ee jarista Guntin lymph iyo qorid ah. Marka ugu of lymphosarcoma erythrocyte ah (ugu yaraan 30 boqolkiiba) ka dhigan unugyada Qarax joogto ah. Iyada oo erythrocytes sida lymphadenitis immunoblastic, sida caadiga ah wax ka yar boqolkiiba 10, ay kala duwan marka la eego basophilia of cytoplasm iyo maturity xuduntii yihiin.

cudurka Histopathological on falanqaynta ee Guntin lymph waa in uu ahaadaa mid aad u faahfaahsan oo laga reebo gabagabo sax ahayn. Maxaa yeelay, histopathology waxbarashada kala duwan ee dhiiga waa in si cad loo qeexo cudurka, oo wuxuu ka tarjumayaa soo gunaanaday. Tusaale ahaan, baaritaanka hore ee lymphoma benign, xaaladaha qaarkood, ilaa wakhti dheer si ay u dhawraan bukaanka iyo mar kale baari qanjidhada.

Cilad-reactions leukemoid looga shakisan yahay marka laga arko immunoglobulin monoclonal mararka qaar u baahan tahay soo noqnoqda iyo indha indheyn muddo-dheer ah oo dalool dhuuxa lafaha. Ka hor ansixinta cudurka of chemotherapy kansarka waa u.

cudurka dhunkashada

cudur kale loo yaqaan Filatov - Pfeyferra, xumad daran taasoo angina monocytic. Waa cudur fayras lagu gartaa lymphocyte Isbadal qaraxa, qanjidhada balaartay iyo beeryarada, lymphadenitis Waxyeelo, dhacdo ee unugyada dhiigga cas gaar ah ee dhiigga durugsan. Wakiilka sababaya waxaa loo arkaa inay virus Epstein-Barr. The salaysan cudurka - Isbadal qaraxa of limfosaytis sababa caabuq fayras gaar ah.

Xaaladda caafimaad oo waa ka duwan yahay. In fudud rhinitt ay sabab u tahay in la jebiyey. Tilmaamo Bannaanbaxa:

• angina ( "cunaha gubanaya");
• wayneeyo of caajisnimo iyo dheecaanka qanjidhada iyo sidoo kale xanuun;
• sanka neefsashada adag tahay in maalmaha hore ee cudurka ay sabab u tahay barar xabka.

Status of dhiigga: kordhay boqolkiiba eosinophils, limfosaytis iyo monocytes.

dhibaatooyin

Lagama maarmaan ah oo ku filan gabagabeeyo tilmaame cudurka waa ay joogaan in asalka mononuclear dhiigga (in ka badan 10-20%) - unugyada kala duwan xuduntii lymphocyte cytoplasm basophilic weyn oo ballaadhan la midab lilac leh aragti perinuclear dhawaaqaa. reactions leukemoid Last in carruurta iyo dadka waaweyn muddo dhowr toddobaad ah, laakiin bilood sii xaaladaha qaarkood, caadi ah ee xaaladda dhiigga.

Iyo soo noqoshada lagu arkay la khafiif ah, mararka qaarkood dura dhowr sano ka dib markii ugu horeysay muddo ba'an. Dhibaatooyinka ka mid noqon kara:

• hepatitis ba'an;
• encephalitis,
• Agranulocytosis;
• dillaac splenic sababa midhihiisa degdeg ah;
• hemolysis shalalka.

Therapy reactions leukemoid

Sida caadiga ah, bukaanada aan u baahnayn daawo gaar ah, sababta oo ah dhawr maalmood calaamadaha ugu muhiimsan ee cudurka baaba'aan iyo gobolka ee dhiigga si caadi ah. Marka sii dheerayn xanuun iyo bukaanka dareemaan xanuunsan loo isticmaalo daaweynta pathogenetic - u xil "prednisolone" at dose oo ah 20-30 mg maalintii ama daroogo kale glucocorticoid si loo baabi'iyo reaction leukemoid. Daaweynta kiis kasta, kaliya magacaabay khabiir ku ah.

Odoroska

Sida caadiga ah positive: faafinta, ma aha sare, sidaa darteed bukaanka aan loo baahnayn karantiil. Si kastaba ha ahaatee, aad u khatar ah dillaac of caajisnimo ah. Dayactirka hoos mugga ay go'aamiyeen qaababka muuqaalka kore ee jirka iyo ka lumay ee angina oo caadi ah heerkulka jidhka. Haddii mononucleosis faafa lagu muujiyey qaab hepatitis, bukaanka loo baahan yahay in isbitaal.