Metaplasia mindhicirka caloosha, calaamadaha, daaweynta. metaplasia Squamous - a ...

Dad badan ayaa laga helay cudurada sida metaplasia xiidmaha gastric, taas oo ah waxa lagu gartaa xumaanshaha of epithelium gastric ee xiidmaha ka. Hydrochloric acid waa la soo saaray unugyada parietal joojin si ay u qabtaan oo ay u shaqeeyaan, oon ku bilaabaan inay ku xanuunsado xubnaha dheefshiidka iyo Dheef loo jeediyo.

Xaaladda qofka haddii ay dhacdo in cudurka noocan oo kale ah waxaa loo arkaa inay halis ah, laakiin la daaweyn karaa. Haddii halkii unugyada caloosha ay dhacdo taranka unugyada colon, waxaa la tixgeliyaa xaalad precancerous. Inkasta oo daaweyn ay dhacdo in this iyo waxa suurto gal ah, laakiin noocyada sare jirto saadaal ah mid aad u liita.

Waa maxay metaplasia mindhicirka?

Tani waa cudur ay unugyada xabka gastric lagu bedelay unugyada xiidmaha. Waayo, markii ugu horeysay ee cudurka ayaa lagu tilmaamay in ka badan 100 sano ka hor by Professor Kupfer. cudurada Tani waa inta badan saameeyaa dadka waayeelka ah. Sida laga soo xigtay tirakoob, 80% bukaannada leeyihiin gastritis chronic iyo boog dyspepsia.

In dadka caafimaadka qaba, unugyada iyo dedkeeda derbiyada caloosha, oo dhan la simay. Haddii dhaawac dhacdaa, unugyada bilaabaan inay si aada u kala qaybiyaan, taasoo keentay in an ay socdaalka iyo soo kabashada cusboonaysiinta gacanta wanaajiyey. Tani geeddi-socodka ee bukaanka qaba gastritis chronic dhibtay, sababtoo ah taas oo qanjirka gastric la joojiyay si ay u qabtaan hawlo ka, taasoo keentay in formation of metaplasia.

noocyada cudurada

Metaplasia ee caloosha waa laba nooc:

• mindhicirka yar (complete, baaluq);
• Colonic (dhamaystirnayn, qaan gaadhin).

foomka baaluq waxa lagu gartaa joogitaanka unugyada kaas oo noqon kara oo kaliya in xiidmaha yar-yar: sulfamutsiny, limbic, enterocytes fijaan. Si kastaba ha ahaatee, feature ugu muhiimsan in Xaqiijiyay In noocan ah cudurada waxaa loo arkaa unugyada Paneth. unugyada caloosha bilaabaan inay eg xiidmaha yar sida qaabka iyo guryaha functional.

metaplasia qaan gaadhin ee caloosha waxaa lagu gartaa koriinkedu daciif ah iyo horumarinta ee qanjidhada gastric iyo epithelium waxaa inta badan wakiil unugyada xiidanka.

Waa in aad ogaato in kansarka gastric in 94% ka mid ah xaaladaha la ogaado metaplasia dhamaystirnayn. xaaladda noocan oo kale ah waxaa loo arkaa inay precancerous, dib u daaweynta waxaa la dilaa.

Intaa waxaa dheer, waxaa xusid mudan metaplasia gaar ahaan squamous. Ina keena aynu fiiriyaa si faahfaahsan.

Waa maxay metaplasia squamous?

feature A of cudurada waa in meel ka mid ah epithelium caadiga ah lakabka heerarka squamous waxaa la aasaasay. At ay asaasiga ah, waa geedi socod lagu bedelay unugyada aadka u kala baaluq yar baaluq. Arintaan waxay leeyihiin awooda wayn si ay u qabsadaan, sida inta badan loo beddelaa mid ka mid ah noocyada unugyada in ay leeyihiin iska caabin sare si ay arrimo waxyeello kala duwan ee.

Tusaale ahaan, metaplasia epithelial squamous of boogaha caloosha gastric caawisaa dabciyo saamaynta waxyeello of falgalka iyo xad-dhaaf acid. Marka irritant waa lagaa saarayaa, nudaha soo laabtay ay gobolka caadiga ah.

Si kastaba ha ahaatee, sida calaamad oo ah habka bahal metaplasia noocan oo kale had iyo jeer uma arrimaha dhibka. Tani waxay keenaysaa in xaqiiqda ah in unugyada aan weli qaan gaadhin, isku dayayaan in ay qabsadaan, bilaabaan in ay isku uruursadaan tiro badan oo ah Isbedelo hiddo iyo waa ma sii awoodi karaan in la xakameeyo ay kala qeybinta, bedalayo kansarka substrate.

Waa maxay sababta uu dhici karaa metaplasia?

cudurka waxa ay sababahan soo socda:

• caabuq xuubka caloosha sababa kala duwan ee arrimaha,
• bararka joogtada ah ee unugyada hunguriga,
• stress joogto ah;
• xanuunada hormoon;
• cuncun of mareenka caloosha iyo mindhicirka,
• gastritis, iyo Wabiyadan socota muddo dheer.

Sidee cudurka isu muujiyay?

Waa cudur laftiisa in sinaba uma muuqato, iyo dhammaan calaamadaha metaplasia caadiga ah ee la xiriira cudurada ayaa qeyb ka ah horumarinta. Kuwaas waxaa ka mid ah:

• lalabo,
• rabitaanka cuntada oo luma;
• xanuun iyo caqlitagid ee gobolka gaastari.

Kordhinta ashitada caloosha waxaa ku weheliyay reflux acid, xanuunka "gaajaysan", ay awoodaan in ay koraan in habeenkii. Haddii metaplasia xiidmaha weheliyay tuuraa hunguriga ku jira gastric, ayaa laga yaabaa inuu matag iyo qadhaadh oo afka.

Baadhista xanuunada

Si loo garto foomka cudurka, fuliyay imtixaan histological. Waa in ee jirka aadanaha ka gogo 'yar oo unug yimaadaan oo lagu bartay. bowd Habka ama unugyada lagu magacaabo biopsy. Qaabkan cudurka waxaa loo tixgeliyaa looga baahan yahay haddii uu jiro tuhun ah oo kansar.

Si loo go'aamiyo heerka waxyeellada mareenka caloosha iyo mindhicirka, cilmi baaris dheeraad ah waa la fuliyay by yahay qalabka endoscopic. Cadka shaki, wasakheeyey rinjiga gaar ah in gebi ahaanba aan dhib lahayn in ay jidhka bini'aadamka. Marka unugyada waxyeelo, ay u bartaan midab gaar ah, iyo in si cad loo arki karaa microscope ka yar.

Features ee daaweynta

Haddii cudurka metaplasia xiidmaha, daweynta cudurrada this waxaa lagu fuliyaa daawada iyo hab ay dedijiyaan. bukaanka waa in la diiwaan-galiyay in dheefshiidka ah.

daaweynta daawada

Habkan daaweynta loo isticmaalo in arrimaha soo socda:

• in la baabi'iyo cudurka reflux gastroesophageal - cudur lagu gartaa tuuro nidaamsan u kacaa ka kooban hunguriga acidic ee caloosha, sida ay magdhow xabka,
• ka hortagga burooyin aan halis ahayn,
• si loo xakameeyo dheecaan gastric.

Waayo, daaweynta dhakhtarkaaga laga yaabaa qoro dawooyinka soo socda:

• Proton lisidda inhibitors - daawooyinka casriga ah in la yareeyo ashitada gastric. "Omeprazole" daweeyo, "Rabeprazole" "Pantoprazole".
• Laabjeexa ( "Fosfalyugel", "Maalox") - daroogada kor u dhexdhexaadnimada ee Aashito.
• H2 - blockers histamine ( "ranitidine", "cimetidine") - daroogada antisecretory.
• Gastroprotectives - haddii aysidhka kordhay ee caloosha, waxay kaa caawin karaan in ay ka hortagaan burburinta xabka.

qalliin

Haddii daaweynta muxaafidka ah ma keenaan natiijo wanaagsan, ka dibna dhakhtarku ku talin karaa in qaliin. Sidee reebay metaplasia? Tan waxaa loo sameeyaa iyadoo la isticmaalayo qalab gaar ah endoscopic si loo yareeyo heerka uu dhaawac, iyo tan waxa loo yaqaan qaliin yar invasive. Haddii loo baahdo, meesha ay waxyeello gebi ahaanba laga saaray. hab of jeer daaweynta dhowr noocan oo kale ah oo yaraynaysa khatarta ah ee qaababka cudurka kansarka.

ka hortagga

Si looga fogaado dhacdo ee cudurada sida metaplasia mindhicirka, waa in aad u hoggaansamaan tallaabooyin ka hortag ah.

Waxaa lagama maarmaan ah si looga fogaado in muuqaalka kore ee stress, jawaabtaadu mid fiican ku meersan kasta. U hubso in aad si buuxda u dejiso.

Adeec heerka nadaafada ee nafaqada. metaplasia mindhicirka caloosha ma aha oo kaliya Helicobacter bakteeriyada, laakiin sidoo kale cudurada kale. Intaa waxaa dheer, haddii xeerarka nadaafadda lagu xad gudbo, jaaniska helitaanka cuntada lagu sumoobo, in dheeraad ah ka cadhaysiin doonaa xabka gastric.

Sidoo kale waa inaad ku eekaan cunto isku dheeli tiran. Xaaladdan oo kale waxaa lagama maarmaan ah in ay gebi ahaanba ka tanaasulaan bedel kiimikada sida, sida cabitaanka kaarboonta leh,,, cuntooyinka cusbada safeeyey basbaas, hilibka. Waxa fiican inaad ka mid ah in aad cunto cunto, hodan ku fiber cuntada. Waxa ay noqon kartaa noocyo kala duwan oo badarka, khudaarta, iyo geedo yaryar, miraha, rooti laga sarreen ah oo dhan.

gunaanad

Sidaas darteed, waxaan ku ogaaday in metaplasia sida. Tani waa cudur khatar ah oo gacan ka gaysan karaan kansarka caloosha. rafcaanka ku habboon in ay ku takhasusay oo loogu dhaqmayo oo dhan talooyin lagama maarmaan ah oo kaliya u dhigi karaa ama la wiiqo habka burbur.