Borotiinka kaadida. Sababaha waxaa laga yaabaa kala duwan

content protein Celceliska kaadida - waa joogitaanka jajab protein serum, kaas oo la sifeeyo iyada oo derbiyada qubaan in kelyaha. Caadi ahaan, heerka waa in aanay ka badan 0,002 g / l, haddii aad kireysato falanqayn joogtada ah ee subaxdii. Inta lagu jiro maalintii, 50-150 mg borotiinka kaadida - Waa iska caadi ah. Laakiin ay u qaadis iyo protein sare kaadida, sababaha leexashooyinkaasi sida waa in la si xeeldheer in bukaan socod eegtada, gaar ahaan haddii borotiin la Qolol in haweenka uurka leh.

farsamo ee geedi socodka, taasoo kororka xaddiga protein, xuub hoostiisa kelyaha lagu kala qaado, waa halkii adag. Waxaa ka qeyb hyaluronidase. enzyme Tani, marka lagu daro hawlaha kale, jabo mucopolysaccharides ee serum. Kordhinta ay hawlaha kor u permeability ee derbiyada gaddoonka iyo permeability xuub, taas oo uu bilaabo inuu mari Britain protein ah.

Marka protein ah ee kaadida, waxaa laga yaabaa in sababaha dhabta ah (kelyaha) oo been ah (extrarenal). Xaq ama falsity cudurka, oo ay raacsan in nidaamka ku meel gaarka ah ama joogtada ah waxaa lagu buuxin karaa kaliya by dhakhaatiirta.

Waa maxay sababta borotiin laga helo kaadida

The eed synthesizing borotiinada ee jirka aadanaha - waa macluumaad hidde. Waxaa jira in ka hiddo aadanaha ee foomka ah ku suntan. silsilad gaadiidka adag, Avv, iyo Relay xigxiga gaarka ah ee hawlgaladaa keenaysaa in hawlgalka jiritaanka iyo saxda ah ee borotiinada ee jidhka ku jira. Report on mid ka mid ah heerarka kala duwan ee silsilad adag oo transformations isdaba joog ah oo protein galay tamarta taas oo dejisa iyo abaabulo shaqadooda, taasoo keentay in waxa u muuqda in borotiinka kaadida.

Sababaha xadgudubyada sida loo saarin karaa in arrimo transiently ama stably sababa cudurka of function ah ee jirka ku jira. Waa adag tahay in jawaab dhamaystiran siin su'aasha sababta borotiinka kaadida, oo aan xog-ururinta oo dhamaystiran.

Kordhi heerarka protein taraysaa in ay disorder ee wareegga kelyaha:

• cillado horumarinta xididka kelyaha,
• isbedelka ay sabab u tahay saamaynta sun on darbiyada qalintaanka ee kelyaha,
• beddelo sarkhaansan yihiin daroogada (israafka ama aan aqbalo);
• xadgudubyada in hawlaha ka tubules of kelyaha,
• cudurada la iska dhaxlo oo lagu dhasho.

Haddii ay jiraan muddo dheer waa protein kaadida, sababaha laga yaabaa in cudurro kala duwan oo jirka ka mid ah sida cudur dheefshiidka nidaamka, dhiig-yaraan daran, saamaynta gubasho, dhaawac, gaadhista qabow, ama dhibta jidhka ama waayo-aragnimo asalka caadifada xooga badan. Xaaladdan oo kale, cudurku waa qaab ku meel gaadh ah, si wadajir ah ula tirtiridda sababaha ka kaadida tagay protein ah.

Joogtada ah (ama muddo-dheer) joogitaanka borotiin laga helo kaadida (proteinuria) ku leeyahay oo ku saabsan cudurka kelyaha iyo marka calaamadaha kale aan meesha joogin.

sababaha la fili karo borotiinka kaadida

• glomerulonephritis cudurka;
• glomerulosclerosis sabab u ah diabetes;
• in thrombosis vascular kelyaha,
• joogitaanka of kelyaha gabsiiya;
• dhagxaan kellida iyo cudurada kale.

Cilad-iyo daaweynta

borotiin laga helo kaadida waxaa loo arkaa caadi ah ay ka kooban tahay ma in ka badan 50 - 150 mg / maalintiiba. xaddiga cudurka of protein waa u fududahay. Sida caadiga ah, this ee la ogaado by kaadida. Inta lagu jiro maalintii waxa ay kaadinayso on farsamo gaar ah. Falanqaynta ayaa lagu soo noqnoqda in ay ka fogaadaan factor ee random bedeli kara qaabka natiijooyinka la ururiyey.

Si looga fogaado shil at baaritaan waqtiga, daawan nadaafadda ee maacuunta iyo dhaq siilka. Waxa intaa dheer in kaadida caadiga ah waxa la qaban karaa microscopy electron of kelyaha, taas oo ka caawisaa baaro xadgudubyada xuub dhulka hoostiisa, in la kordhiyo tirada of daloolada iyo size.

Gaar ahaan si dhow ula daawanayay heerka borotiin laga helo kaadida haweenka uurka leh, tan iyo markii shaqada kelyaha ah mid qasan by ilmo galeenka sii kordhaya iyo in la kordhiyo load ku on dhan jidhka iyo kelyaha gaar ahaan. Norm dhimay oo waa in aanay noqon ka weyn yahay 0,14 g / l (dayo maran).

Daaweynta cudurka adag oo la xidhiidha hawlaha kelyaha oo yaraada (ama xaaladaha kale ee cudurka laga helay by takhaatiirta) loo samayn karaa oo keliya ee bukaan socod eegtada.