Daawada 'Warfarin'. Tilmaamaha loogu isticmaalo

The daroogada tilmaamaha "Warfarin" loo isticmaalo waxaa loola jeedaa qaybta ka mid ah daawada xinjirowga lidka ku ah ee aan tooska ahayn tallaabo. Daawada waa awoodaa inuu xakameeyo ereygu wuxuu ahaa ee arrimaha xinjirowga (vitamin K-ku tiirsan) iyo sidoo kale protein C iyo S beerka. saamaynta daawada xinjirowga lidka ku fiicnayn arkay maalintii saddexaad ama shanaad ka dib markii bilow ah ee daaweynta iyo joojiyo saddex ilaa shan maalmood ka dib ka dib markii dose ee la soo dhaafay. daroogada waxaa laga heli karaa kiniin.

Waxaa lagu talinayaa marka la qaadanayo daawada "Warfarin" cunto ku lug dayactirka qiyaastii isla xaddi vitamin K cunto

maragga

Daawada waxaa la tilmaamay ee ka hortagga iyo daweynta thrombosis iyo thromboembolism. By muujinaya for daroogada "Warfarin" diiwaanka la xidhiidha thromboembolism iyo thrombosis arooriyaha ba'an, lungemboli, bogsashada ee Wadnaxanuun myocardial, thrombosis postoperative. diyaarinta waxaa loogu fulinta ka kaxayntu ay thromboembolic ama thrombosis qalliinka (sida hab oo dheeraad ah) ee wadne (Wadne artafiishal korontada), noqoshada (dib) xididka thrombosis, lungemboli ee halbowlaha pulmonary. Oo macnaheedu yahay "Warfarin" diiwaanka ku talinaysaa in aalka vascular iyo khaanadaha wadnaha (taas oo la oggol yahay iyadoo la isticmaalayo marka la isku daro ee acetylsalicylic acid). Intaas waxaa sii dheer, daroogada waxaa loogu thrombosis, cerebral, halbowleyaasha wadnaha iyo durugsan, iyo sidoo kale ka hortagga thrombosis sare ah ama gufeysan yar inta lagu jiro bilig bilig ee wadne ama ka dib Wadnaxanuun.

Sababo in gacanta lagu daroogada "Warfarin" edbinta u soocay dulqaad shaqsi, kelyaha ama cudurka cagaarshowga daran, hemorrhage ba'an, hypertension (nooca culus), sii daridda ah ee boogaha caloosha ama malawadka, diathesis hemorrhagic, la'aanta S iyo C borotiinada, Khamriga, hemorrhage cerebral, yaridu function kelyaha, ba'an Indvandrerrådgivningen, Torombositobiiniya. Wuxuu magacaabaa daroogada ah inta aad uurka leedahay.

The dhacdooyinka xun ugu badan ee lagu jiro maamulka daroogada "Warfarin" waa dhiig. Marar dhif ah, waxaa jira galleeyda maqaarka, kor u ensaymes beerka, shuban, canbaar, timaha khasaaro, vaskulitis.

qiyaasta

Daawada waxaa lagu tilmaamay maamulka afka. Talinayo codsiga hal, in waqti isku mid ah. Qiyaasta hore - laba iyo badh ilaa shan milligram per maalintii.

mudada kacmaha Xiga "Warfarin" (INR ama waqti prothrombin markii this waa la tixgeliyaa) waxaa si gaar ah goostay. In labo ilaa afar jeer ka soo isha waa in la sii kordhay markii prothrombin. Xaaladdan oo kale INR ee (ratio caadi caalamiga ah) waa in ay gaaraan (ku xiran tahay cudurada ku itimaalka oo dhiigbax ah, khatar thrombosis) 2.2-4.4.

Bukaanka waayeelka ah ama xaalad wiiqay qoray qaadasho hoose ee daroogada "Warfarin".

Ka hor inta socdo hawlgalka (in ay dhacdo cabista horumarinta dhibaatooyin thromboembolic) therapy bilaabmaa laba ama saddex maalmood ka hor ku lug lahaanshaha.

In daaweynta thrombosis ba'an waxaa lagu fuliyaa ee isku dhafan oo daroogada "heparin" ilaa iyo haatan marka saamaynta daawada xinjirowga lidka waxaa si buuxda ma muujiyey (ka hor maalinta saddexaad iyo shanaad sida caadiga ah ma).

Muddada daaweynta ku xiran tahay xaaladda bukaanka.

Ka hor inta bilowga ah ee daaweynta loo baahan yahay si loo ogaado index INR ah (iyadoo la raacayo waqtiga prothrombin ah, siiyey thromboplastin dareen Wehliyaha ah).

Sida laga soo xigtay dad badan oo buka, daawo "Warfarin" ma aha oo kaliya wax ku ool ah, laakiin sidoo kale ku haboon, maadaama ay u baahan tahay in la qaado oo keliya hal mar maalintii. Intaa waxaa dheer, waxay ka dhigan tahay si fiican loo dulqaatay, waxyeelo waa dhif iyo naadir. Si kastaba ha ahaatee, ka hor inta isticmaalka sheyga, waa in aad takhasus u leh la tasho, oo si taxadir leh u akhri tilmaamaha.