"Cymbalta": tilmaamaha loo isticmaalo. Reviews, qiimaha, tilmaamo

Maanta waxaan kuu sheegi doonaa in uu yahay maandooriye "Cymbalta." Tilmaamaha loogu isticmaalo daroogada, inta ay ka kooban, waxyeelo, iyo akhrinta la hoos lagu qeexay doonaa. Sidoo kale ka soo article soo gudbiyey, waxaad ku baran doonaa oo ku saabsan qaab kaas oo daroogada waxaa laga heli karaa, inta ay ku kici, haddii waxa uu leeyahay contraindication ah iyo sida loo sax ah u codsan.

Form sii daayo

In waxa foomka waxaa ka iibsan kartaa daawada "Cymbalta" barashada kaas oo ku lifaaqan ee xirmadan? Currently daroogada la sii daayay oo kaliya ee foomka of kaabsoosha enteric. Mid kasta oo ka taas oo ka kooban ku kaabsal, kaas oo ay leeyihiin midab cad ama grayish cad.

daroogada

Waa maxay qaybaha ka mid ah daroogada "Cymbalta?" Tilmaamaha isticmaalka kaabsoosha sheegayaa in ay element ugu weyn ee firfircoon yahay duloxetine walax. Sidoo kale waa in la ogaadaa in qaab-dhismeedka medicament u tixgeliyo oo ka mid ah walxaha dheeraad ah sida sucrose, hypromellose, Rusheyn kartaa, succinate, colorant cad, copolymer hypromellose, titanium dioxide, sitraydh triethyl, gelatin, sodium lauryl sulfate iyo jaalaha Midabka xabagta bir ah.

Kaabsulka ku jiri kara 60 iyo 30 daroogada mg. Waxaa loo buuxiyey oo ku yaal finan of 14 ama 7 kaabsulka. In mid ka mid pack kartoonka noqon kartaa 1, 2 ama 6 finan.

sifooyinka pharmacological daroogada

Waa maxay walaxda firfircoon sida duloxetine? Tilmaamaha isticmaalka kaabsoosha, daawooyinka dhigayaa in jilitaanka noocan oo kale ah daroogada la element sheegay waa mid aad u niyad jabka wanaagsan. Waa inhibitor ah reuptake ee norepinephrine iyo serotonin. Waxa uu kullanka uu hakiyo qaadashada dopamine iyo buuna u lahayn in ay dopamine, histamine, iyo receptors adrenergic holino-.

Sidee Duloxetine? Hagaha waxaa ku jira macluumaadka soo socda ku saabsan arrintan, mabda'a of tallaabo oo ah walaxda waa in la xakameeyo reuptake of norepinephrine iyo serotonin. Sidaas darteed, si weyn u kordhiyaa noradrenergic iyo neurotransmission serotonergic in habka dareemayaasha jirka. Sidoo kale waa in la ogaadaa in duloxetine si deg deg ah loo xakameeyo xanuunka.

Pharmacokinetics daroogada

Daawooyinka murugada ah "Cymbalta" ka mareenka caloosha iyo mindhicirka nuugo, nuugista bilaabo dhowr saacadood ka dib markii maamulka. fiirsashada ugu badan waxaa lagu gaarayaa 6 saacadood ka dib. soo dhaweynta wadajira oo cunto ah wax saameyn ah kuma fiirsashada iyo kordhiyaa waqtiga si ay u gaaraan a 6 ilaa 10 saacadood. Khubarada ay sheegayaan in si dadban ay yaraynaysaa heerka uu nuugista (11%).

Qabanaya daroogada borotiinka plasma waa heer sare ah oo ku filan iyo gaadho in ka badan 90%.

Nolosha nus ka mid ah daroogada waa 12 saacadood. Isla mar ahaantaana soo gelayoba kaadida sida metabolites.

Sida laga soo xigtay waxbarashada, waxaa jira farqi u dhexeeya geedi socodka pharmacokinetic ka dhaca ragga iyo dumarka ah. Sayidka, ansixin celceliska qayb firfircoon hoos jinsi ah caddaallad ah. Si kastaba ha ahaatee, qiyaasta sixitaanka muhiim ma aha.

Sidoo kale waa in la ogaadaa in faraqa u dhexeeya geedi socodka pharmacokinetic ka dhaca bukaanka dadka waayeelka ah iyo da'da dhexe ee la sameeyay intii uu baaritaanka. Waxay shaaca ka qaaday in bar-nolosha ee daroogada waa sare ee dadka waayeelka ah ka badan dadka dhalinyarada ah. No sixitaanka qiyaasta looma baahna midkood.

In bukaanka qaba la'aan kelyaha chronic ee stage terminal, kuwaas on dialysis, fiirsashada of qaab iyo midowga afrika ee duloxetine korodhka at dhab ahaan 2 jeer. Taasi waa sababta ay waxaa lagu talinayaa in la tixgeliyo advisability ee yareeyo qiyaasta daawada ee bukaanka qaba itaaldarro daran ee function kelyaha.

Bukaanka qaba calaamadaha beerka u dhigi karaan metabolism iyo tirtiridda bar-nolosha ee duloxetine.

Tilmaamayaasha isticmaalka lacagta

Marka qorayaasha "Cymbalta?" Tilmaamaha loogu isticmaalo waxaa ka mid ah liiska soo socda ee akhrinta:

• qaabka neuropathy xanuunka macaanka,
• dalalka niyad-jabka iyo niyad;
• ciladda wallaaca guud;
• xanuun joogto ah syndrome muruqyada, oo ay ku jiraan kuwa ay keento fibromyalgi iyo osteoarthritis.

Sababo in loo isticmaalin lacagaha

Marka aad ma qaadan kartaa daawooyinka "Cymbalta?" Tilmaamaha loogu isticmaalo waxaa ka mid ah liiska soo socda ee sababo:

• codsiga isku mar ah inhibitors awood of CYP1A2 isoenzyme (tus, enoxacin, ciprofloxacin ama fluvoxamine);
• dareenka kor u bukaan macnaheedu waa qaybaha;
• carruurta ka yar 18 sano jir,
• soo dhaweynta haatan la MAO;
• hypertension halbowle waa reer caasiyoobay,
• glaucoma xiritaanka bedelo,
• daran renal failure raaga (la CC wax ka yar 30 ml / min);
• deficiency isomaltase ama saccharase, nuugeynin glucose-galactose iyo dulqaad fructose;
• cudurrada beerka in waxaa weheliya la'aan cagaarshowga.

Marka waa in la isticmaalaa daroogada taxaddar

Waa in la isticmaalaa si taxadir leh u sheegay in daroogada ee cudurka laba-cirifoodka iyo waali, halista gariir gulukooma weerar xagal-xiro. Sidoo kale, daryeelka waa in loo qaato dhiig karka marka indhaha, fikradaha isdilka, hyponatremia, beerka iyo kelyaha.

Drug "Cymbalta": tilmaamaha loo isticmaalo

Qiimaha alaabta this waa mid aad u sarreeya. Si kastaba ha ahaatee, ah waxtarkeeda ma hoos gasho wax shaki ah.

daawo soo bandhigay waxaa lagu soo qoray oo kaliya maamulka afka. kaabsoosha waa in la wada liqo oo aan burburiyo ama u qaadka. Waa in la ogaadaa in ay dhacdo in kasta oo aan lagu dari karaa si daroogada ama cunto ku daraan wax cabitaan ah, tan iyo markii ficilkan oo kale si fudud waxyeeli kara daahan ee enteric.

Daawooyinka murugada waa in la qaato qiyaasta hore ee 60 mg maalintii hal mar. Si loo gaaro natiijo wanaagsan in bukaanka qaar ka mid ah in la kordhiyo lacagta la sheegay in dose oo ah ugu badnaan 120 mg laba jeer maalintii.

Bukaanka qaba cudurka kelyaha chronic, taas oo dhacda in marxaladda terminal, qiyaasta hore ee medicament waa 30 mg maalintii hal mar. Haddii bukaanka waxay leeyihiin cillad beerka, xaddiga tilmaamay daroogada lagu talinayaa in hoos loo yareeyo ama badnaanta isku soo dhaweynta.

Sidoo kale waa in la ogaadaa in si looga fogaado in bixitaanka kadis helo medicament. xaddiga daroogada loo baahan yahay si loo yareeyo si tartiib ah in ka badan 1-2 toddobaad. Haddii asalka this, waxaa jira calaamado fahmayaan of syndrome ah, waxaa lagu talinayaa in ay sii wadaan daaweyn in qiyaasta loo qoondeeyey. Ka dibna, waxaa laga yaabaa in dhakhtarku wadaa inuu hoos u qiyaasta, laakiin si tartiib ah.

xaaladood oo badinta

Maxay khubarada yidhaahdo oo ku saabsan xaaladaha badinta daroogada, "Cymbalta?" Reviews dhakhaatiir ku jira macluumaad in xogta sida la heli karo iyaga. Si aad u taariikhda, waxaa jira xaalado ah qiyaasta xad dhaafka by xammil daroogada ee xaddi ilaa 3000 mg, iyo marka lagu daro wakiilada kale. Waana mid ka, oo go'an iyo mid dhimasho.

Calaamadaha badinta ama go'doon isku daro waxaa ka mid ah xaaladda soo socda: gariir clonic, somnolence, matag, kooma, serotonin syndrome iyo tachycardia. Sida cilmi preclinical (tijaabo on xayawaanka), calaamadaha ugu muhiimsan ee sumoobo la xidhiidha aqbaliddoodii caasiyoobay medicament, waa cudurada of nidaamka neerfaha iyo dheefshiidka dhexe. Sidoo kale, bukaanka u muuqan kara gariirka, ataxia, gariir clonic, matag iyo rabitaanka cuntada oo luma.

Waxa la sameeyo haddii ay dhacdo of badinta? Iyadoo horumarinta serotonin syndrome waa in isla markiiba la fuliyay cyproheptadine therapy saxayo, iyo sidoo kale habka loo isticmaalaa in lagu caadiga heerkulka jirka bukaanka.

bukaanka waxaa laga rabaa in ay bixiyaan hawo cusub. Sidoo kale waa inaad socdo shaqada wadnaha iyo socdo calaamadaha muhiimka ah. Waxaas oo dhan waa in la sameeyaa in lala taageerada qabashada iyo daaweynta calaamadaha.

Haddii ka dib markii maamulka daroogada aan ahaa muddo dheer, waxaa lagama maarmaan ah in ay ku dhaq soo baxay caloosha. Sidoo kale, si ay u yareen daawada bukaanka laga codsaday in ay cabbaan dhuxusha firfircoonaan.

dhibaato

saamayn taban ku leh caafimaadka dadka hesho daawo odhan karaa? Tixgeli dhibaatooyinka soo raaca daawooyinka lidka diiqadda in faahfaahin dheeraad ah:

• Inta badan (10% ee kiisaska) ee waxbarashada clinical, bukaanka leeyihiin dalalka soo socda: wareer, madax xanuun, afka oo qalala, hurdo la'aan, hurdo la'aan, lallabo, hurdo iyo calool.
• total ka yar (1 ilaa 10% ee kiisaska) bukaan ayaa la arkay biyo-raaciska, shuban, aragga indhaha oo isku darsamay, matag, dhidid, gariirka, anorgasmia kordhay, rabitaanka cuntada oo hoos u, luminta libido, miisaanka oo yaraada, daal, kacsi, iyo sidoo kale dib u dhigto ama biyo bax aan caadi ahayn.

Waxaan ma dhihi karo in waxyeelo sida dawakhaad (mararka qaarkood madax xanuun iyo yalaalugo), badanaa loo arkaa la joojiyo kadis ah medicament ah. By habka, in bukaanka qaba foomamka neuropathy diabetic xanuun badan la kulmi karaan in la kordhiyo sonkorta dhiigga calool madhan.

Reviews of medicament

Sida laga soo xigtay ku takhasusay, iyo bukaanka daawo loo tixgeliyaa si buuxda ula qabsadaan hawsha. Marka la helo waxa ay meesha ciladda wallaaca, iyo sidoo kale kor u lumay ee dalalka niyad. Intaa waxaa dheer, iyo sidoo medicament firfircoon oo Fayda Xumaanta syndromes xanuun nidaamka muruqyada.

Dhexgalka siyaabo kale

waxaa suurtagal ah in wada-Maamulka daroogooyinka kale daawo "Cymbalta?" khubaro Guest sheegaya in hab ku yidhi waa saameyn toos ah ku waxtarka dawooyinka qaar ka mid ah.

Sidaas, waxaa jira halis of serotonin syndrome, duloxetine haddii loo isticmaalo isku dhafan oo MAOIs.

Maxaa yeelay, isoenzyme CYP1A2 waxaa si firfircoon uga qayb-shiid ah "Cymbalta 'diyaarinta, isticmaalkooda isku mar waxay keeni kartaa in ay isugu soo urureen kordhay doonana.

Aan lagula talinayaa medicament ayaa sheegay in wada daawooyin kale oo waxyeela habdhiska dareenka dhexe. Sidoo kale intii uu ogolaado waa in cabbin aalkolo.

Mararka qaarkood, halka isticmaalka SSRIs iyo wakiilada serotonergic ee bukaanka lagu arkay serotonin syndrome. Sidaa darteed, waa in aad jimicsi taxaddar dheeraad ah marka la isticmaalayo daroogada la murugada serotonergic.

Sababo la xaqiiqada ah in ay jirto khatar ka iman kara korodhka dhiig waa in aan u isticmaali duloxetine iyo daawada xinjirowga (antithrombotics) labadaba.

Naas-nuujinta iyo uurka

Ma isticmaali karaa daawada "Cymbalta", qiimaha kuwaas oo lagu soo bandhigi doonaa on, inta lagu guda jiro uurka? Sababo la helid la'aanta macluumaad ku filan, isticmaalka duloxetine maalkii inta lagu guda jiro uurka daawada laga yaabaa in lagu maamulo kaliya haddii lacagta hooyada uurka leh waa ka sii badan halis u ah ilmaha.

Sidoo kale waa in la ogaadaa in bukaanka qaadanaya wakiilka waa hubi inaad soo sheegto dhakhtarkaaga dhacdo ama uur yeelato.

Daraasado ayaa muujiyey in haweenka qaadashada daawooyinka murugada ee gobolka, gaar ahaan marxaladaha ugu dambeeya, si weyn u kordhiyaa halista ah ee hypertension pulmonary joogto ah oo ka mid ah carruurta dhasha. Xaaladdan oo kale, syndrome ayaa sidoo kale inta badan lagu arkaa carruurta ay dhacdo stop kadis ah oo isticmaalaya hooyadiis duloxetine mustaqbalka marxalad soo daahay ee uurka. Inta badan calaamadaha xaaladan ayaa lagu arkay marka ay dhalayso ama in ka maalmood ee ugu horreeya ka dib.

Maxaa yeelay, duloxetine waa ay awoodaan in ay dhex gasho galay caanaha naaska, ma aha la jecel yahay in ilmaha la nuujiyo naaska inta lagu jiro daaweynta. Haddii kale, fiirsashada oo ah walaxda in ilmaha caloosha ku noqon doonaa caddad of 0,14% of-fiirsashada ee hooyada.

hanuun gaar ah oo ku saabsan isticmaalka daroogada

By loo qoondeeyo daroogada si uu bukaan-socodka "Cymbalta", dhakhtarka waxaa waajib ku ah inay isaga u sheegtaa in si cad uu mamnuucayaa gelitaanka hal mar ah wakiilka la MAO ah. Haddii kale, waxaa ay halis gelin kartaa dhibaatooyin dhimasho iyo halis ah oo hyperthermia, myoclonus iyo guurka excitation muujiyay galay kooma.

Sidoo kale waa in la ogaadaa in ay xaaraan helaan daawo muddo labo isbuuc ah ka dib markii daaweyn sheegay MAO.

Sida laga soo xigtay waxbarashada, in bukaanka qaba gobolka manic marka la isticmaalayo daroogada kale oo waxyeela habdhiska dareemayaasha jirka, in lala tahay "Cymbalta" sii dari kara cudurka jira.

Sababo la xaqiiqada ah in gobolada niyad jirto suurtagalnimada ah isku day is miidaamin ah, waa in si gaar ah loola socdo bukaanka ka tirsan kooxda halista ah.

Aqbalaada daroogada wuxuu noqon karaa mid fudud in ay hurdo keenaan. Sidaa darteed, bukaanka qaata daroogada this, waa in aad is ogow dheeraad ah markii baabuur-wadidda iyo markii la mishiino dhaqaaqaan khatar shaqeeya.

Price iyo analogues daroogada

Sidee badan yihiin "Cymbalta" kaabsoosha enteric? Qiimahoodii kala duwanaan karaan. Waxay ku xidhan tahay soo saaraha iyo xadad silsilado farmashiyaha. Si kastaba ha ahaatee, waxaa la ogaadaa in celcelis ahaan, daroogada kharash ah oo ku saabsan 1,050 rubles Ruush (30 mg, 14 xabbadood). Haddii aad u baahan tahay si aad u iibsato dawo in tiro la mid ah, laakiin qiyaasta ah 60 mg, ka dibna waxaad u baahan doontaa inaad bixiso ku saabsan 1150 rubles.

Hadda oo aad ogtahay inta duloxetine. Its qiimaha kordhin karaa ama hoos u dhac ku xiran tahay arrimo gaar ah. Currently, iibka waxaa loo yaqaan daroogada ma aha wax dhib ah. Si kastaba ha ahaatee, aad ka iibsan kartaa oo kaliya by qoro.

Laakiin waxa haddii aad sabab qaar ka mid ah ma aysan awoodin in ay iibsadaan a "Cymbalta" kaabsoosha, daawooyinka? Analogs daroogada this waxaa laga helaa farmashiyaha shiidaa kasta. Inkastoo helitaanka sidoo kale u baahan doonaa jiritaanka warqad dhakhtar.

Daawada waxaa lagu beddeli karaa "Cymbalta?" Ka mid ah facooda uu jeclaan lahaa in aan si gaar ah loo muujiyo daawooyinka soo socda:

• "Intro";
• "Azafen" (kiniin);
• "Duloxetine Canon" (kaabsoosha Enteric);
• "Venlafaxine Sandoz";
• "Alvent";
• "Mirtazapine Canon";
• "Eprobemide" (xal in / iyo / m ah);
• "Wellbutrin";
• kiniiniyada "Eprobemide";
• "Agomelatine";
• "Neyroplant";
• "Velafaks";
• "Calixtus";
• "Venlaksor";
• "Vensuert";
• "Dapfiks";
• "Venlift guutada";
• "Despres ';
• "Efevelon faafiyo";
• "Doppelgerts Nervotonik" sida elixir ah;
• "Inkazana";
• "Efevelon";
• "Coaxil";
• "Esprital";
• "Lerivon";
• "Trittiko";
• "Normazidol";
• "Mirzaten";
• "Tetrindol";
• "Mirtazonal";
• "Remeron";
• "Mirtalan";
• "Pirazidol";
• "Negrustin";
• "Nyuvelong";
• "Noksibel".

Habka of kaydinta iyo shelf-nolosha

Waa maxay nolosha shelf ee daroogada ah "Cymbalta?" Sida laga soo xigtay tilmaamaha, iyo taariikhda on baakada, qalab this waa in aan la qaadan muddo saddex sano ah. Xaaladdan oo kale waa in lagu kaydiyaa meel gudcur ah, halkaas oo heerkulka kama badna 20 degrees.