Sanka buufin "Dezrinit": dib u eegista dhakhaatiir, tilmaamaha loo isticmaalo iyo halabuurka

"Dezrinit" - glucocorticosteroid dardaro (GCS) codsi la mariyo. Wakiilka firfircoon waa mometasone tallaabo antiallergic iyo antiinflammatory. In codsanaya daroogada ee qiyaasood oo aan keeni saamaynta systemic mariyo ay anti-bararka hawlaha la mariyo. Tixgeli qodobkan ku saabsan "Dezrinit" jawaab diyaarinta ka dhakhaatiirta iyo macaamiisha.

Daawada dhaxalsiiyeen sii daayo dhexdhexaadiyayaal bararka, kor u lipomodulin wax soo saarka, waa inhibitor ah phospholipase A, kanna waa ay sabab u tahay hoos u of acid iyo Avv prostaglandin Iscelin la sii daayay arachidonic iyo endoperoxides xilliile ah. Daawada waa in laga hortago raasamaal ee neutrophils, yaraynta soo saarka ee exudate bararka iyo lymphokine, Iscelin of socdaalka qorayo, yareynta geeddi granulation iyo dhexgalka, yaraynta formation of chemotaxis, ie saamayn ku dareen-celin ka dib xasaasiyad dhacdaa joojiyaan horumarinta dareen-celin alerji deg dega ah.

Tani waxaa xaqiijiyay medicament ah "Dezrinit 'dib u eegista dhakhaatiir - takhasusay ay duurka. hab-dhismeedka ka mid ah furoate mometasone iyo auxiliaries.

Pharmacokinetics

codsiga Intranasal yaraynaysaa bioavailability systemic ee furoate mometasone in ka yar 1%. walax firfircoon heli karo dhiiga, in tiro yar oo u nuugo oo si firfircoon biotransformed pass ugu horeysay iyada oo beerka ka dib. On diyaarinta "Dezrinit" Dhakhaatiirta dib u eegista intooda badan wanaagsan.

Waxa lagu tilmaamayaa, waayo,

• daaweynta carruurta dilka ah iyo xilliyada rhinitt xasaasiyad ka 2 sano iyo wixii ka weyn iyo dadka waaweyn,
• hogaga ba'an, sii daridda carruurta hogaga chronic laba iyo toban sano jir iyo wixii ka weyn, iyo dadka waaweyn (oo ay ku jiraan dadka waayeelka ah) sida daaweynta Curiyaha taageerada ah oo la isticmaalayo antibiyootiko,
• daaweynta adenoids carruurta ama dadka waaweyn polyposis sanka,
• ka hortagga rhinitt xasaasiyad xilliyeed ee xaaladaha meeldhexaad ah ama daran carruurta laba iyo toban sano jir iyo wixii ka weyn iyo sidoo kale dadka waaweyn. Anshaxa lagu talinayaa in afar todobaad ka hor bilowga xilli ciyaareedka masaxaaya.

Form sii daayo

sanka lagu buufiyo mitir. Mid ka mid ah waxay fijaankeedii ku jira 140 qaadasho. foomka tixraaca ee daroogada ee foomka of dhibco ka jirin inta lagu jiro waqtiga diyaarinta daabacaadan. Habboon ee carruurta "Dezrinit". Reviews dhakhaatiir u xaqiijin.

Habka isticmaalka iyo tilmaamaha loo isticmaalo

Daawada waxaa maamula intranasally. Buufiyo ku jira weelka lagu mudaa sanka la isticmaalayo qalab kacmaha gaar ah.

Ka hor inta bilowga codsiga ah ee lagu buufiyo si ay u sameeyaan 10 qasabadaha imtixaanka on qalab raan. Ka dib markii dhaqmaan, heerka dhalmada daawada lagu wadaa, jaraa'id kasta tirsan Isbahysiga ganaax of 100 mg oo ay ku qoran 50 mikrogram mometasone. Ka hor inta isticmaalka sheyga ka dib markii in ka badan fasax 14 maalmood ah, dhaqmaan waa in lagu celiyo. Codsi kastaa waa inuu la socdaa hordhac gariir weelka.

waxyeellooyin

About "Dezrinit» Diyaargaraw dib u eegista caafimaadka soo jeedin dhibaatooyinka suurogal soo socda:

• glaucoma,
• reactions diidmo oo ay ku jiraan dyspnea, iyo bronchospasm;
• anaphylaxis;
• madax xanuun in carruurta iyo dadka waaweyn,
• anjioedema,
• sangoror,
• gubanaya of dalool sanka,
• caruurta la kulmi karaan koritaanka faaqidaad, fawdada ah psychomotor, hurdo xumo, walwal, dabeecadaha gardarada ah, niyad jab,
• cune xanuun,
• daloolin ee septum sanka ,
• dareen ah cuncun of-axaleedka ee saabka sanka,
• dareen cuncun xabka pharyngeal;
• caabuqyada neef-mareenka sare,
• hindhiso,
• dhadhamin qas;
• xad gudub ku ah dareenka urta,
• tirey,
• kordhay cadaadiska intraocular;
• ulceration xabka ee saabka sanka.

sababo

Drug "Dezrinit" (dib u eegista ah ee dhakhaatiirta waxa ay xaqiijin) waa u in:

• diidmo in mometasone ama qayb ka mid ah samaynta;
• .. A qalliin dhawaan ama dhaawacyada sanka in dhaawacaa bogsashada, in u dhaqmo si GCS hab inhibitory at bogsiinaya geedi socodka;
• carruurta (haddii polyposis sanka 18, exacerbations ba'an ee hogaga chronic, ba'an ama ilaa 12 sano, da'doodu tahay 2 rhinitt la xasaasiyad dilka ah iyo xiliga la socota).

Isticmaalka daroogada xilliga uurka iyo nuujinta

Gaar ahaan lahayn waxbarashada isticmaalka ammaan ah "Dezrinita" xilliga uurka iyo nuujinta la sameeyay. daroogada Tani waa in la siiyo naas-nuujinta iyo haweenka uurka leh oo keliya haddii faa'iidooyinka caafimaad hooyada badnayn halista ka iman karta in ilmaha ama uurjiifka. Dhallaanka ay hooyadood isticmaalo corticosteroids inta aad uurka leedahay, aad u baahan tahay si ay u gudbaan baaris gaar ah si ay u aqoonsadaan suurto gal hypoadrenalism. Tani waxaa xaqiijiyay medicament ee dib u eegista ee immunology caafimaad "Dezrinit".

Isticmaalka daroogada ee carruurta

Isticmaalka "Dezrinita" waa u in carruurta la polyposis sanka dalool 18; sii daridda ah ee hogaga chronic ama foomka ba'an ee ilaa 12 sano; la rhinitt xasaasiyad dilka ah iyo xilliyeedka ilaa 2 sano. Inta badan loo isticmaalo "Dezrinit" in adenoids carruurta. Reviews dhakhaatiir saaraysa fiican.

tilmaamaha loo isticmaalo

Calaamadaha atrophy xabka sanka daaweynta hal sano (12 bilood) ka dib markii aan la arkay. Daraasad ee jarista xabka sanka muujiyeen saamaynta mometasone in dhaqankan cusub ee caadi ah histology. Isticmaalka muddada dheer ee daroogada, iyo sidoo kale wixii daawayn waqti-dheer, waxay ku lug leedahay kormeerka wareegsan sanka Laryngologie dhakhtar xabka.

In marinka hawada qaaxada (huruda ama firfircoon); bakteeriyo, fayras systemic (oo ay ku jiraan herpes saameeyaa indhaha, ama simplex Herpes) ama caabuq fangas, daaweynta dheer by corticosteroids; joogitaanka caabuq aan la daweyn goosgoos ah xabka sanka, iyo sidoo kale naas-nuujinta iyo uurka, daroogada waa qori si taxadir leh.

Daaweynta waxay ka dhigan tahay "Dezrinit" talinaynaa in ay joojiyaan oo ay bilaabaan in ay sameeyaan daaweynta gaarka ah ee horumarinta cudurka degaanka fangas of dalqada ama sanka.

Lur ee dalqada iyo sanka saabka, kaas oo sii socoto muddo aad u dheer, waa la tixgelin karaa calaamad u ah failure of daroogada. Waxaad sidoo kale qori kartaa in la ma shaaca ka qaaday xakamaynta nidaamka hypothalamic-pituitary-adrenal ka dib isticmaalka daba dheeraaday ee daroogada. Tani waa caddaynta ku reviews ee diyaarinta "Dezrinit".

fiiro gaar ah laftiisa ay u baahan yihiin bukaanlayda qaadato daawada dheer la corticosteroids, marayo daawaynta mometasone. Hadii aad joojisid tallaabada nidaamka GCS, markaas fursad waxaan dhihi karaa in ay ka dhigi doonaa in la'aanta ah ee shaqo adrenal, daaweynta kuwaas oo u baahan doonaan tallaabooyinka ku habboon.

In bukaanka qaar ka mid ah, kala guurka ah si ay daweyn mometasone ka dib markii corticosteroids dhici kara astaamaha u-barashada isticmaalka systemic ee glucocorticosteroids. Waxaa ka mid ah niyad-jabka, daal, xanuun murqaha iyo / ama kala-goysyada. Bukaan-socodka u baahan gaar ah ka dhaadhiciyo daaweyn in la "Dezrinit" waa ku haboon, inkastoo ay hoos u ee darnaanta calaamadaha lesions xabka sanka. Duubtay (laakiin mar horeba jirtay in bukaanka) daaweynta cudurrada glucocorticoid xasaasiyad systemic sida canbaar iyo conjunctivitis, loo aqoonsado la kala guurka ah si ay corticosteroids maxaliga ah.

In daaweynta polyps gooni; polyps, kuwaas oo xiriir la leh cystic fibrosis, iyo polyps, si buuxda u dabooli dalool sanka, ammaanka iyo waxtarka ah "Dezrinita" aan la bartay. Dhiigbaxa iyo polyps gooni isagoo qaab ah aan joogto ahayn, waxaa lagama maarmaan ah in ay sii baaraan.

Bukaanlayda qaadato therapy by corticosteroids, heli falcelin la dhimay difaaca oo sidaas daraaddeed waa dig iyaga in ay kordhiyaan halista cudurka la taabto jadeecada buka, busbuska iyo qaar ka mid ah nooca kale ee faafa cudurka, iyo baahida loo qabo in la tasho dhakhtar takhasus u leh, haddii xiriir la leh bukaan-weli anna waxaan soo qaaday meel.

isticmaalka daba dheeraaday ee corticosteroids sanka in qiyaasood oo waaweyn ay noqon karaan qaar kaaliya ee horumarka ah ee waxyeellooyin. Si kastaba ha ahaatee, saamaynta u noqon karaan meel fog ka yar tahay marka corticosteroids systemic waxaa loo isticmaalaa, oo ku kala duwan yihiin in bukaanka shaqsi. saamaynta systemic la fili karo waxaa ka mid ah Cushing ee syndrome, taas oo ah waxa lagu gartaa xakamaynta adrenal, glaucoma, caadka, dhimaal koritaanka carruurta iyo dhallinyarada, iyo mararka qaarkood tiro ka mid ah saamaynta dabeecadeed iyo mid nafsaani, oo ay ku jiraan walaac, dhibaato hurdo, niyad-jabka ama gardarada, fawdada ah psychomotor.

Sida dhexgalka daroogada dhexeeya daawooyin kala duwan la mometasone ah, oo ku saabsan cilmi la sameeyay.

sanka lagu buufiyo «Teva Dezrinit": dib u eegista macaamiisha iyo dhakhaatiirta

Reviews of diyaarinta inta badan wanaagsan. caawimo wanaagsan la rhinitt xasaasiyad. Caadi ahaan dhif dulqaadan siiyo waxyeelo. Carruurta yar yar waxay ka caawisaa in adenoids, yaraynaysaa bararka. Waxa ugu weyn ee ay ixtiraamaan tilmaamaha loo isticmaalo.