"Rosuvastatin": tilmaamaha loo isticmaalo, dib u eegista. analoogga Cheap "rosuvastatin"

Daawada "Rosuvastatin" yaqaano 2003 iyo waxaa loo jeediyaa sida a Generation statin IV. Waa inhibitor casri ah oo tayo sare leh ee reductase gamma-methylglutaryl-CoA. enzyme Tani waxay masuul ka tahay ereygu wuxuu ahaa ee kolestaroolka ee jirka aadanaha. Its Iscelin keenaysaa in la yareeyo ee kolestaroolka qoomiyadda iyo in la yareeyo halista cudurka wadnaha.

Waxa intaa dheer in "rosuvastatin" waxaa jira dhowr dhigooda fasalka, xubno ka tirsan kooxda statin ah. Tani "dawo" "Pravastatin", "cerivastatin," "Lovastatin," "Fluvastatin," "Atorvastatin", "pitavastatin." oggolyahay Clinical iyo xawaaraha yareynta kolesteroolka iyo low-cufnaanta total "Rosuvastatin" kaliya "pitavastatin," taas oo aan weli si weyn loo isticmaalaa sabab u database yar u ururay ee tijaabo.

Si aad u taariikhda, "atorvastatin" waxaa loo isticmaalaa inta badan statins kale maxaa yeelay waa caddaynta saldhig cilmi ugu ballaadhan ee ay waxtarka bukaan ah. Sidoo kale, isaga iyo xabbo waa wax badan ka jaban, "rosuvastatin". Laakiin sida saamayn ugu dambeeya (caadi ah profile la egyahay ee plasma dhiigga) waa ka dhaqso, oo uu bilaabo in la codsado sii ballaadhan. Tani waa wax soo saarka si dhab ah oo tayo leh, kaas oo waa in ay bixiso qiimaha.

Saar "rosuvastatin" in dawooyin

In diyaarinta "Rosuvastatin" codsiga, inkastoo jiritaanka dhigooda fasalka, si caddaalad ah ballaadhan. Waxaa lagu qeexay tilmaamo iyo sababo ku koobnayn. muujinaya waa la joogo in ku dhowaad dhammaan noocyada kala duwan ee hypercholesterolemia iyo cudura-shiid la egyahay. The hoos u atherogenic jajabyada la egyahay leeyihiin saamayn togan ku u shaqeeyo. Taas darteed, suurtagalnimada of horumarinta lesions atherosclerotic waa la dhimay, iyo cimri (iyo tayada) xoogaa kordhiyo.

Diyaarinta "Rosuvastatin" ayaa loo isticmaali karaa ka hortaga cudurada wadnaha, iyo in ay iyaga daaweeyo. dawooyin Misbaax Last jira ay sabab u Dulmiga geedi socodkii atherosclerosis iyo xasilinta endothelial of huurada. Tan iyo Wadnaxanuun cerebral iyo wadnaha horumariyo ka thrombosis ba'an taasoo keentay halbowlayaasha, ka dibna saamaynta caafimaad oo run ahaantii waxay ka caawisaa si looga hortago dhacdooyinka coronary ba'an.

Tilmaamaha loogu isticmaalo

Lifaaqsan daroogada "Rosuvastatin" diiwaanka (analogues dukumentiyada sida la heli karo) waxaa ku jira kala duwan cidhiidhi ah ee muujinaya in loo isticmaalo. Si kastaba ha ahaatee, waxa aanu ku jira wixii macluumaad ah ee bukaanka in loo baahan yahay ka hor in la isticmaalo si loo ogaado jajabka ee kolestaroolka. In mustaqbalka, ay isbedel qiimeyn doonaa waxtarka caafimaad ee daaweynta ee qiyaasta gaar ah. Sidoo kale bayaan ka kooban yahay macluumaad ku saabsan tallaabooyinka nabadgelyo iyo muuqaalada daaweynta, sababo, iyo dhibaatooyinka ugu badan oo la taaban karo.

Tilmaamayaasha

Ka mid ah dhammaan cudurada la xiriira kor u jajabyada la egyahay plasma, muujineysaa qaar ka mid ah tilmaamo caafimaad oo:

• dhaxlo heterozygous (qoyska) hypercholesterolemia;
• lagu tilmaamay inay by Fredrickson IIa nooca hypercholesterolemia polygenic;
• dyslipidemia isku daro, lagu tilmaamay inay by Fredrickson sida IIb;
• Saarku hypercholesterolemia (qoyska) Homozygous;
• wadnaha, maskaxda ama kelyaha arteriosclerosis, occluding Lumen ee halbowlaha ah,
• Atherosclerosis of the xididdada oo ka mid ah jirka ka hooseeya, oo ay ku jiraan Leriche syndrome ,
• (Nooca IV sida ay Fredrickson) hypertriglyceridemia;
• daaweynta Wadnaxanuun myocardial iyo maskaxda, tan iyo xilliga ba'an;
• ka hortagga Wadnaxanuun myocardial iyo stroke.

sababo

Kasta oo analog "rosuvastatin" jaban waxay leedahay dhibaatooyinka la mid ah sida "Crestor" asalka ah. On ku salaysan sababo spectrum ay la aasaasay, taasoo waa sida soo socota:

• cudurka syndrome cytolysis cagaarshowga la hepatocytes iyo koror ka badan saddex-laab uruureen transaminase;
• beerka, cirrhosis la dhibcaha ee 9-Child Pugh;
• hawlaha chronic renal failure tilmaame la ansixin kariyaatiniin ka yar 30 ml \ min.,
• Myopathy asal kasta;
• cadaanyo in qaybaha dejinta ama "Rosuvastatin".

Waxaa jira koox sababo kale oo qiyaasta 40 mg:

• renal failure raaga la ansixin kariyaatiniin tilmaame aan ka yarayn 60 ml \ min.,
• wax myopathies dhaxlo;
• isticmaalka saameen leh fibrates;
• khamriga,
• tartanka Mongoloid;
• isticmaali of statin ah markii ugu horeysay.

Features of daroogada

All "rosuvastatin" - daroogada, analogues kuwaas oo si balaadhan looga heli karo suuqa. Oo by dooranaya magac brand gaar ah, bukaan-socodka waa in ay qaataan daawada oo ku saabsan. In uu yahay, bedesho daawo kale aan macquul ahayn. Sam daroogada waxa laga soo qaatay oo aan la eegin in cunto wakhti kasta oo ah maalintii. Waxaa jira dhawr talo oo kale oo khubaro ah, kuwaas oo markii hore la soo shaqeeyay ee statins jiilka kowaad. Waxaa ku jira macluumaad in statins waa in la qaato wakhtiga hurdada. Inkasta oo aanay ahayn muhiim, in alaale inta daawada laga qaaday ee ku saabsan waqti isku mid ah iyo si joogto ah.

Xakamee ay gobolka u gaar ah waa in ay ahaadaan si joogto ah ilaa aqbalay "Rosuvastatin" (analogues). Reviews ogolaan khubaro in ay ka shaqeeyaan xeeladaha ugu fiican ee loogu fiirsado. Gaar ahaan, ka dib markii la aasaaso joogitaanka hypercholesterolemia leeyihiin si ay u bilaabaan qaadashada daroogada la qiyaas go'an. 2 bilood ka dib markii lala socdo - lipidogram si joogta ah loo sameeyaa oo la qiimeeyo waxqabadka of aminotransferases.

Haddii uu jiro caadi ah profile la egyahay ee plasma dhiigga, waxaa loo baahan yahay in ay sii wadaan la helo in dose isku. Haddii kolestaroolkaaga guud uu yahay mid sare, iyo qadarka cholesterol cufnaanta hooseeyo si weyn u dhimay, kordhinta qiyaasta loo baahan yahay. Haddii transaminase saddex jeer kor u kacay, waxay u baahan tahay ka saarida statins. Waa in la ogaadaa in si gaar ah u janjeera ugu yar in ay keeni cytolysis oo dhan statins waa "Rosuvastatin." Analogs (Ukraine ayaa sidoo kale si tartiib ah u wareegaayo ka "atorvastatin" in "rosuvastatin") class yar aamin ah. A "pitavastatin" weli ugu yaraan ku bartay.

Analogs "rosuvastatin"

Sida isbarbardhig, "rosuvastatin" ( "Crestor") mar hore waxay bixisaa in ka badan 10 alaabta. iyaga ka mid ah, "AKORT", "Merten", "Rozart", "Rozistark" "Rosuvastatin Canon", "Rosuvastatin SOTEX" "Rosuvastatin NW", "Rozulip", "Rozukard", "Roxer", "Rustor" " Tevastor ". Qiimaha dhaqmaya waa kala duwan, iyo sidoo kale ku-oolnimada. Qiimo daawooyinkaan loo qaybin karaa saddex qaybood:

• Qiimaha hooseeya (laga bilaabo 250 ilaa 650 rubles), "Rosuvastatin NW", "Rosuvastatin Canon", "AKORT" "Rosuvastatin SOTEX";
• qiimaha caadiga ah (400 900 rubles), "Merten", "Rozart", "Roxer", "Rozukard", "Tevastor", "Rozulip";
• qiimaha sare (laga bilaabo 1100 in 2200 rubles): "Crestor".

Falanqaynta qiimaha waxaa sameeya is barbar kharashka daawooyinka, miisaanka of xarunta firfircoon oo ahaa 10mg. kala duwan oo qiimaha uu ka tarjumayaa qiimaha hal bil ah therapy cholesterol-hoos. The analog "rosuvastatin" jaban macmalay by "Northern Star". "Rosuvastatin Canon" iyo "AKORT" sidoo kale waa wax yar oo kala duwan qiimaha. Ay qiimaha waa yar tahay in la beddelo ku xiran tahay isbeddelka heerka sarrifka.

muuqaalka guud ee generic "CRESTOR" jaban

The daroogada "Rosuvastatin" daayay by Astrazeneca, waxaa loo yaqaan "Crestor". Tani waa dawo asalka ah, oo waa in la barbar dhigo kuwa kale oo dhan. Isla sidaas u dhaqmaan comments: sifo ah ee wax soo saarka gaar ah generic waa in lagu saleeyaa ay la "Krestorom" barbardhigo. Laakiin sababta oo ah kharashka xad sare, bukaanno badan isla markiiba bilaabaan daaweynta hypercholesterolemia la xabbo jaban.

macluumaad Ujeeddo kaliya khabiiro ku siin kara in dib u eegis ah, kuwaas oo inta badan soo food leh isticmaalka xabbo oo "rosuvastatin" iyo "CRESTOR" asalka ah. A codsatay in ay daroogada "Rosuvastatin 'tilmaamaha loo isticmaalo, Kurtumm bukaanka iyo waayo-aragnimo caafimaad oo ogolaan doona in bukaanada kale si ay u doortaan magac ganacsiga gaar ah.

Reviews oo khaas ah "Crestor" iyo xabbo

Isbarbardhigga "CRESTOR" fuliyay oo kaliya by takhasus of Society Ruush ee Wadnaha. Macluumaadkaan waxaa inta badan soo daabacay wargeyska "dawooyin QUMMAN ee wadnaha." Gaar ahaan, waxa la hadlaya arrimaha bioequivalence daroogada generic "Crestor". Sida laga soo xigtay natiijooyinka daraasaadka pharmacoeconomic ayaa muujiyay in daroogo "Merten", "Rozart", "Roxer", "Rozukard" iyo "Rozulip" "Crestor" bioequivalent.

Taas macnaheedu waa in wax kasta oo "rosuvastatin" eegtahay waxa uu leeyahay saamayn ku daweyn la mid ah daroogada asalka uu leeyahay tiro isku mid ah iyo adkaanta waxyeelo. Inkasta oo daawooyinka "Rosuvastatin NW", "Rosuvastatin Canon", "Rosuvastatin SOTEX" iyo "AKORT" in baaritaan sida aan loo isticmaalin. Sababtoo ah, kuwaas oo waxbarashada tirakoobka aan maalgeliya shirkadaha dawooyinka, macluumaadka keentay waa ujeedada iyo buuxiyey astaamaha caafimaad ee daaweynta ee hypercholesterolemia. Si kastaba ha ahaatee, natiijada keliya ee xabbo shisheeye.

Reviews of xirfadlayaasha xabbo cheap "rosuvastatin"

analoogga Modern of a "rosuvastatin" cheap waa caddeeyaan bioequivalence "Crestor" ka dibna waxaa si toos ah uu helo ixtiraam ee xirfadlayaasha. Haddii aan cilmiga bioequivalence khubaro u sheegi kartaa oo kaliya sifooyinka caafimaad ee codsiga. Mid ka mid ah iyaga ka mid ah waa kan: haddii loo isticmaalo si joogta ah dhigooda jaban "rosuvastatin" (daawooyinka kor ku xusan), soo noqnoqoshada dhacdooyinka xun dhigma in lagu arkay marka la isticmaalayo bioequivalent generic "Crestor".

Degidda fiirsashada plasma "rosuvastatin" ka kacay isticmaalka foomka qiyaasta adag leh Halabuurka kala duwan, waxaa loo arkaa qiimo lahayn kiiskan. Maxaa yeelay, analoogga cheap Ruush ah "rosuvastatin" run ahaantii bedeli karaa daroogada "Crestor" asalka ah iyo daawooyin ay generic lagu daaweyn jiray hypercholesterolemia.

Astaamaha u gaarka ah dib u eegista bukaanada

Sida laga soo xigtay jawaabaha dadka bukaanka ah oo wadaaga dareenkaa ku saabsan isticmaalka daroogada dhakhtarkaaga, waxaa jira dhowr gunaanad macquul ah. Marka hore, bukaanka xukummadayda ku saabsan tayada daawada u janjeedhaan. Marka labaad, maxaa yeelay, dismo in ay saamaynta caafimaad ee bukaan-socodka u hogaansanaanta therapy ay yar tahay, inkasta oo daaweyn loo baahan yahay si looga hortago khatarta ah in dhacdooyinka coronary ba'an. Saddexaad, bukaanka u muuqdaan in ay ka badbadin muhiimadda ay leedahay dhibaalka dhanka kale iyo dhayalsan, dhaq-profile la egyahay plasma.