Niyad jabka 'Azafen', tilmaamaha loo isticmaalo, waxyeellooyin

Drug "Azafen" waxa loola jeedaa koox ee ugu murugada tricyclic. Waxay leedahay dejinaysaa sare, anxiolytic iyo saamaynta antiaggressive. daroogada Tani waxaa si balaadhan loo isticmaalo daweynta ee sambabada iyo Niyadjabka sare, sida:

- qoomiyadda,

- astenodepressiya;

- exogenous;

- khamriga,

- alarm;

- state inta lagu guda jiro xaaladaha degaaankaaga ee dabiiciga ah ee joogtada ah.

Walaxda firfircoon ee daroogada "Azafen" description loola jeedaa pipofezine. hab ay of tallaabo walax ku salaysan Iscelin of qaadashada neuronal of norepinephrine iyo serotonin. Tani waxay keenaysaa in la kordhiyo fiirsashada of pipofezine in habdhiska iyo astaamaha niyad jaray.

Waxaa jira hal faa'ido ama ka badan daroogada la mid ah garoomada daroogada niyad jabka tilmaamaha "Azafen" loo isticmaalo waxaa loola jeedaa in maqnaanshaha saamaynta ay cardiotoxic. Waxaa la xusay sida saamayn togan oo macnaheedu yahay "Azafen" on xanuunada affective, wiiqday xanuunada degaaankaaga ah, eegay autonomic la xidhiidha niyad-jabka. oggolyahay High "Azafen" diiwaanka qeexayaa ka dhanka ah asthenia, dhibaatooyin timi sabab u tahay soo gunaanadeen aadanaha degaaankaaga. Inta lagu jiro maamulka daroogada ee bukaanka baaba'aa welwel, stress. dhaqdhaqaaqa wanaagsan in bukaanka qaba, tusale, hurdo caadi ah iyo hurdo u baaba'aa inta lagu jiro maalinta.

Daawo "Azafen", oo ku salaysan guryaha ay pharmacokinetic ayaa digestibility wanaagsan, waxaa lagu si wanaagsan u nuugo iyada oo marinka dheef shiidka, ayaa bioavailability sare (80%), fiirsashada dhiigga ugu badan hore u gaadho 2 saacadood gudahood. In beerka ku dhacdaa by pipofezine biotransformation si aan firfircooneyn metabolites in waxaa lagu soo bandhigaa in kelyaha. sii daayo Full daroogada jidhka ka dhacdaa 16 saacadood gudahood.

Daaweynta buufiska ee asal ahaan kala duwan oo ay calaamad u ah aasaas u ah isticmaalka daroogada buuga "Azafen" edbinta ku qeexan yihiin gobolka, taxay dhammaan noocyada depressioy, bandhigi daroogada.

Waxaa jira sababo dhowr ah hesho niyad jabka tilmaamaha "Azafen" loo isticmaalo si ay u muujiyaan dalalka soo socda ma aha waafaqsan daaweynta daroogada:

- diabetes;

- wadaaga la MAO ;

- Wadnaxanuun myocardial, wadnaha, cudurka halbowlaha wadnaha,

- cagaarshowga ama renal failure;

- cudurada faafa, oo daran;

- state ka dib markii shil halis ah cerebrovascular (stroke);

- Uurka, nuujinta.

Waa in dhawrsada dhacdo suurto galka ah ee waxyeelo inta lagu guda jiro daawaynta, waxay muujiyeen by wareer iyo madax xanuun, dareen diidmo oo xasaasiyadeed, matag iyo lallabo. Nasiib darro, ma jiraan wax macluumaad ah oo ku saabsan daaweynta ee case of badinta daroogada, in kiisaska noocaas ah, waxa ay qaadataa astaamaha. On arrinta sababo waa in lagu daraa dhibaato la mid ah "Azafen" iyo khamriga. Kuwan waxaa laba fikradaha si buuxda u wada gaar ah inta lagu guda jiro daawaynta waa in la joojiyo ka cabbo khamriga iyo soo dhaweynta isku mar ah diyaarinta ka kooban ethanol.

The "azafen" ma aanan helin guryaha anticholinergic, ee ha quusan daaweynta daawada loogu talagalay dadka qaba gulukooma. Intaas waxaa sii dheer in aynan khamriga, waxaa jira halis of codsiga isku mar daroogada daawada xinjirowga lidka, xasaasiyadda iyo daroogada oo dhan, habdhiska niyadjabka. Fadlan la soco in soo dhaweynta isku mar ah "azafen" daawooyin antiepileptic yareeyo waxtarka dambaysta ah.

Sii daayay "Azafen" si adag sida ay la karinayo, nolosha shelf ugu badnaan waa 5 sano, waa in lagu kaydiyaa at tmax 25.