The habka iyo tilmaamaha loo isticmaalo "Loraksona". Analogs iyo dib u eegis

Waa maxay daroogadu sida "Lorakson 500" oo kale ah? Tilmaamaha loogu isticmaalo, sifooyinka of qalab ah, iyo sidoo kale in ay calaamad u, qaab, oo sideeda oo analogs ayaa hoos looga hadlay.

Baako, qaabka, halabuurka ka mid ah daroogada

Waa maxay qaabka waa dabeecadda dawada loo arkaa? Maxaa sharcigan ayaa sheegay in gacanta lagu bartaa? "Lorakson" waa budada crystalline ah oo cad ama wax yar ka hurdi, loogu talagalay diyaarinta of xal mudayo sinta ama xidid. Halabuurka The of medicament ka mid ah qayb firfircoon sida ceftriaxone. Waxaa la soo bandhigay qaab ay cusbo sodium.

Sidoo kale, daroogada "Lorakson" diiwaanka kaas oo ku jira in xidhmooyin baakado ka mid ah dareeraha ah sida biyo la isku duro.

diyaarinta mawduuca la soo saaray ee fijaan oo dhalooyinka of 10 ml oo waxaa lagu dhejiyay in sanduuqyada warqad (waxaa laga yaabaa in la iibiyo leh ama aan lahayn dareeraha ah).

Daawooyinka Pharmaceutical Products

Waa maxay daawada sheegnay? Waa maxay macluumaadka ku jira tilmaamaha loo isticmaalo? "Lorakson" - ah antibiotic (cephalosporin) qarnigooda saddexaad, loogu talagalay maamulka parenteral. Waxay leedahay tallaabo bactericidal.

Iyada oo awood u leh inay la xakameeyo ereygu wuxuu ahaa ee xuubka unug ka mid ah daroogada uu hakiyo koritaanka ugu sheyga Gram-negative iyo Gram-positive.

Sida laga soo xigtay khubaro ah, ceftriaxone muujinaysaa xasiloonida gaar ahaan ka dhanka ah beta-lactamase (penicillinase, cephalosporinase), kuwaas oo la soo saaray bakteeriyada badan.

Kinetics daroogada

Sidee Lagu Daweyn faafo wax soo saarka on jidhka bini'aadamka ah? Maxay waxan leeyahay tilmaamaha la socda loo isticmaalo? "Lorakson" on maamulka parenteral si fiican yahay galeen ku dhowaad dhammaan unugyada iyo dheecaannada jidhka.

Iyada oo faleebo xididka of ceftriaxone si deg deg ah soo jiidasho leh diffuses dareeraha interstitial, halkaas oo guryaha ay lid ku ah bakteeriyada lagu hayo maalintii oo dhan.

Waa in la sidoo kale xusay in qayb firfircoon ee wakiilka reversibly xidhxidhan albumin. Sababtoo ah content yar ee dambe ee dareeraha interstitial, fiirsashada of daroogada waxa ku jira wax yar ka badan ee serum ah.

In waxa la eego daroogada waxaa laga bukaan? Waxa uu sheegaayo oo ku saabsan tilmaamaha loo isticmaalo? "Lorakson» kuwaas oo ka kooban kor ku xusan ayaa lagu wada hadlay, waxaa soo bandhigay 8 saacadood (la socdaan bile iyo kaadida). Sidoo kale waa in la ogaadaa in sarkhaansan oo ka mid ah flora xiidmaha ee element firfircoon oo qalab la bedelay si ay u metabolite ah firfircoonayn.

In dhallaanka dhashay, bar-nolosha waxaa loo arkaa daroogada of 8 maalmood, iyo dadka waayeelka ah (ka weyn 70 sano), muddo this waa 2 jeer ka badan.

The kinetics daroogada in xaalado gaar ah

Marka ayna nidaamka kelyaha iyo beerka heley ee dadka waaweyn aadanuhu ku pharmacokinetics of ceftriaxone ficil ahaan waa iska beddelin, muddo nus-nolosha waxaa dheeraado ma maarmaanka ah.

Marka shaqada kelyaha waxaa si weyn u dhimay, tirtiridda daroogada qaadataa meel inta badan la bile, laakiin haddii ay waxyeello beerka, ceftriaxone ee inta badan soo minguuriyey via kelyaha.

In ilmaha iyo dhalaanka barar ku dhaca xuubka ku medicament this geli karin dareeraha lafdhabarka. In dadka waaweyn ee meningitis 5-25 saacadood ka dib markii maamulka ka dib markii at qiyaasta ah ceftriaxone 50 mg / kg miisaankiisa jirka dhowr jeer ay fiirsashada ka badan MIC ah, taas oo looga baahan yahay xakamaynta bakteeriyada taas oo keeni cudurka.

maragga

Goorma ayaan la isku duro daroogada "Lorakson 500" la sameeyo? Tilmaamaha loogu isticmaalo (irbado waa in la siiyaa oo kaliya dhakhtar khibrad leh) ayaa sheegay in daroogada waxaa loogu talagalay in lagu daweeyo cudurada faafa iyo bararka oo ay keento bakteeriyada xasaasi u ah daroogada. Sidaas darteed, waxaa si firfircoon loo isticmaalaa in:

• meningitis,
• cudurada of mareenka sare,
• sepsis;
• cudurada kaadi mareenka iyo kelyaha,
• cudurada nidaamka taranka (oo ay ku jiraan jabtada);
• cudurada caloosha (oo ay ku jiraan cudurada bararka ee xiidmaha, peritonitis ah, cudurka biliary mareenka);
• cudurada maqaarka,
• cudurada of mareenka-mareenka (oo ay ku jiraan pneumonia);
• cudurada, unugyada wadajirka iyo lafta,
• cudurada dadka qaba difaac hoos.

Sidoo kale, hab yaabaa in loo tixgeliyo tilmaamay ka hortagga ah ee lesions faafa ee muddada postoperative.

Mamnuucay ballanta

Ma jiraan wax sababo daawooyin sheegnay? Waxa uu sheegaayo tilmaamaha la socda loo isticmaalo? "Lorakson" muujinaya oo lagu kor ku xusan, waa in aan la qoro in arrimaha soo socda:

• Samir diidmo in benisiliinta iyo cephalosporins;
• in bilaha ugu horreeya uurka.

Iyada oo digniin dawadan waxaa lagu talinayaa in la siiyo dadka qaba cudurka beerka, ulcerös iyo enteritis. Sidoo kale, taxadar waa in loogu dhaqmaa marka NUC, hyperbilirubinemia ee ilmaha dhashay in labada trimester ee uurka ugu dambeysa, caruurta dhiciska iyo naas-nuujinta.

Tilmaamaha loogu isticmaalo

"Lorakson" maamula bukaanada intravenously ama intramuscularly. qiyaasta celceliska maalin kasta ee daawada loogu talagalay dadka waaweyn iyo carruurta 12 sano jirka ah waa 1-2 g mar maalin kasta (24 saacadood ee kasta).

Xaaladaha daran, iyo sidoo kale cudurada in waxa sababa wareer ah dhexdhexaad ah oo xasaasi ah, dose maalinle ah wakiilka this lagu kordhin karaa ilaa 4 g

caruurta dhawaan ku dhashay maamulka 1 time daroogada halkii maalintii waxaa lagu talinayaa in qiyaasta soo socda: 20-50 mg / kg (ilaa 2 todobaad jir).

baradka Baby iyo carruurta jirta ilaa 12 sano, qiyaasta maalin kasta waa in ay ahaataa 20-75 mg / kg. Caruurta qaangaarka ahi la miisaanka jidhka of 50 kg medicament qaadashada maamula ee dadka waaweyn.

Muddada aad daawada by hab this ku xiran tahay cudurka.

Shuruudaha diyaarinta xal

Sida loo diyaariyo xal daroogada? Maxaa sharcigan ayaa sheegay in gacanta lagu bartaa? "Lorakson" foomka sii daayo ayaa lagu kor ku soo bandhigay, waayo, duridda waa in lagu qasi (1 g) ee 3.5 ml oo ah 1% - xal of lidocaine, ka dibna si qoto dheer galaan muruqa Salalka ah.

Si aad u diyaariso samaynta a la isku duro xididka, 1 g oo ah budada ah waa in lagu qasi 10 ml debeda, biyo (sterile). Xalka kama dambaysta ah waa in la tartiib ah soo bandhigay xididka (4 daqiiqo).

Waayo, faleebo xididka of 2 g of daroogada ee loo baahan yahay si ay u milmaan in 40 ml of xal (tus, chloride sodium, dextrose ama fructose), oo lacag la'aan ah ka calcium. faleebo Tani waa in la sameeyaa ugu yaraan kala bar hal saac.

Ifafaale by-qof

Ma falcelinta negative xal daroogada "Lorakson" ah? Tilmaamaha loogu isticmaalo (irbado waa in la sameeyaa oo keliya ee isbitaalka a) doodaysaa in ee macnaha guud ee la isticmaalayo daawada this bukaanka waxaa laga yaabaa in la horumariyo:

• lalabo, leukopenia iyo matag, granulocytopenia, shuban, hypocoagulation, caloosha oo, dhiig hemolytic, yaaqyaaqsi, lymphopenia;
• calool-xanuun, phlebitis, qas dhadhanka, xanuunka ay weheliyaan xididka, stomatitis, urtikaria, glossitis, neutropenia ah;
• enterocolitis pseudomembranous, dhexgalka iyo danqasho goobta maamulka muruqyada dhexdooda, beerka oo yaraada,
• function kelyaha oo yaraada, goiter, thrombocytosis, glycosuria, Torombositobiiniya, oliguria, finan, azotemia, bronchospasm;
• siyaadiyaa HOL in dhiig, eosinophilia, hypercreatininemia ah, erythema polymorphic, cylinduria, goror, hematuria, superinfection, anuria;
• qandho, bukaanka serum, qandho, anjioedema, pruritus, dawakhaad, shoog, candidiasis, madax xanuun.

Iskaashiga iyo xaaladood oo badinta

Iska badinta lacagta lagu muujiyey wareer, madax-xanuun, paresthesia, gariir, encephalopathy iyo kooma. Si aad u baabi'iyo ifafaale codsan daaweynta calaamadaha, iyo taageeraya hawlaha muhiimka ah ee jirka.

daaweynta isku mar la ceftriaxone la aminoglycosides Kordhiyey hawlaha bakteeriyada. Si looga hortago saamaynta sun ah wakiilada kuwaas waxaa maamula waqtiyo kala duwan iyo meelo kala duwan.

Waxaa loo adeegsaday in isku midka ah "Loraksona" inhibitors xulkii balataleetyo iyo NSAIDs waxaa jira halis sare oo dhiig.

Marka aad hesho a diuretics "loop", waxaa jira halis weyn oo nephrotoxicity.

Viewed daawo leheyn ethanol, sida isku darka this sababa lallabo daran, dubaaxin ee gobolka gaastari, matag, bafinayo, hoos u cadaadiska dhiigga iyo tachycardia.

Waa arin mamnuuc ah in nooca in ceftriaxone mid silingaha iyo antibiotics kale.

daawooyinka la mid ah iyo warcelin on daawo

Haatan waad garanaysaan waxa a "Lorakson". Tilmaamaha loogu isticmaalo, waxay ka dhigan tahay analogs waxaa looga hadlay this article.

Maxaa bedeli karaa daawada? Waayo, daawooyinka la mid ah khubarada tixgeli arrimaha soo socda: "ceftriaxone-Promed" "ceftriaxone-dartaa," "Tsefogram", "Tsefson" "ceftriaxone-Protekh" "ceftriaxone-Dzhodas", "Tseftriabol", "Tsefatrin".

Sida laga soo xigtay jawaabaha dadka bukaanka ah, inta badan ka hadlaya hab ay loo isticmaalo in lagu daaweeyo cudurrada neef-mareenka sare iyo caabuqyada neef-mareenka. Falanqaynta fariimaha ay, waxaan si ammaan ah ku tirinnaa karaa in ay tallaabo degdeg ah oo wax ku-oolnimada sare. Sidoo kale waa in la ogaadaa in marka la isticmaalayo daroogada this in qaar ka mid ah bukaanka waxaa jiray waxyeelo fudud in aan u baahneyn joojiyo dawaynta.