The daroogada "Divigel": dib u eegista, sharaxaada, codsiga

gel-ring "Divigel", dib u eegista ah kuwaas oo aad u tiro badan, waa daroogada dardaro protivoklimaktericheskim loogu calaamadaha deficiency estrogen ba'an. By ay dabiicadda waa hab of hormone replacement therapy, sida ay walax firfircoon - estradiol dardaro - marka la eego kiimikada iyo noolaha gabi ahaanba isku mid u hormoonnada jinsiga ee dumarka ee dabiiciga ah.

The daroogada "Divigel", dib u eegista ah kuwaas oo inta badan fiican, waa heer sare ah wax ku ool ah muddo dheer ama daaweynta meerto haweenka ee muddada postmenstrual. Maaddaama ay dheecaan ku filneyn of estrogen wajiga this waxaa jira u sobob kala duwan ee u shaqeeyo, disorder hurdo muujiyey, xasilooni vasomotor, atrophy horusocod nidaamka Fistula, iyo inta badan dhabarta osteoporotic. Saameyn aad u la mid ah tallaabada of hormone dabiiciga ah, iyo madadaalo horumarinta siilka, dhuumaha ugxanta iyo diyaarinta galeenka "Divigel" (ratings u xaqiijin) gabi ahaanba ay meesha ama si weyn u yaraynaysaa symptomatology this.

Pharmacodynamics of gel waa sida soo socota. In unugyada kuwaas oo lagu by daroogada "Divigel" estradiol dardaro galo xidhi kiimikada la receptors gaar ah, la xirrira iyaga la receptor-ligand adag iyo la dhaqanka qaybaha estrageneffektornymi hiddawadayaasha, iyo sidoo kale borotiinada intracellular gaar ah. Taasina waxay keentaa in induction ee ereygu wuxuu ahaa ee mRNA iyo sii daayo cytokines kala duwan.

Sayidka, ring macnaheedu yahay "Divigel" dhiiri diidmada waqtiga iyo joogto ah oo dhiig-bax ah daahirintiisa oo siiban. fiirsashada badan oo daroogada kor laga yaabaa in kelyaha gooba, xakamaynta of nuujinta, Iscelin of resorption unugyada lafuhu, iyo in ay kicin Avv gaadiidka qaarkood borotiinada (tyroksiini globulin ku qabanaya, transcortin, transferrin).

Codsiga External macnaheedu yahay "Divigel" (markhaati furayaa, warcelin this) ayaa ku dhowaad ma saamayn kooxda sida dhiig kar. Sida xaqiiqada ah tanu waa faa'iido weyn marka la barbardhigo daawooyinka afka estradiolsoderzhaschimi kala duwan.

Means maamul-ring "Divigel" IVF lagu qoro marka waxaa loo baahan yahay in la joogteeyo heerka loo baahan yahay ee estradiol. Qaadashada sare shaqsi iyo waxaa go'aamiya rugta takhasuska halkaas oo nidaamka la sameeyay. waxbarashada Clinical "Divigel" daroogada go'aamiyo nooca ay waafaqsan iyo in la dhexgalo daroogooyinka kale. Hadaba, waxa ogaaday in ay qayb firfircoon waxay yareyn kartaa waxtarka antihypertensive, daawooyinka antidiabetic iyo xinjirowga lidka ku ah. Maamulka wadajira ee wakiilada iyo diyaar garowga ay ku jiraan inductors iyo falgalka beerka (barbiturates, "carbamazepine" "griseofulvin" "Rifampicin", iwm) waxay keeni kartaa hoos u dhac estradiol ee plasma dhiigga.

Habka daaweynta "Divigel" daroogada, taas oo qiimaha waa arrin dhexdhexaad ah, waa in uu la socdaa sahan joogto ah. Joogtaynta iyo qeexayaa set oo ah dhakhtar hababka sida ay baahida caafimaad oo shakhsi ah bukaan kasta. Laakiin sida caadiga ah, loo magacaabay by mammography kiisaska intooda badan.

Sida barashada diyaarinta "Divigel" waxa uu leeyahay tiro ka mid ah sababo. Gaar ahaan, cudurka ama xubnaha taranka looga shakisan yahay formation kansarka buro caanaha (fibroids, makaanka, kansarka ilmo galeenka, siilka, ugxan, iwm), kelyaha Endometrial, cudurada waajihi of unugyada connective, climacteric wajiga giperestrogeniey, thrombophlebitis, burooyinka beerka iyo xadgudub pituitary stroke, macaanka iyo cudurrada kale ee. Sidaa darteed, qalabka waa in la qaato kaliya by qoray iyo hoos qiyaasood oo ay si adag u qeexan.