"Teopeka" (300 mg): tilmaamaha loo isticmaalo, tilmaamo, soo saaraha

Dadka qaba neefta, taqaan sida ay muhiim si ay uga caawiyaan la bronchospasm. Mararka qaarkood tallaabada saxda ah ee xaaladda adag ku badbaadin karto noloshooda. doorka A weyn ee helitaanka dadka ka dhibaato sanbabada ciyaaro bronchodilators.

Description of diyaarinta

"Teopeka" (300 mg), tilmaamaha loo isticmaalo kaas oo lagu muujiyay in warqad this waa kiniinada cadcad ee ploskotsilindricheskoy qaab wareeg ah, kuwaas oo buuxiyey oo ku yaal xirxiraan dusha. The qayb weyn ee firfircoon ee daroogada waa theophylline. Its fiirsashada ee kiniin ah hal Diyaargarayska oo foomkan waa 300 mg.

Sidee dawadan?

By ay tallaabo pharmacological of theophylline, taas oo derivative ah purine, saamayn anada on phosphodiesterase ah. Walaxda firfircoon ee blocks daroogada receptors purine gaar ah, wuxuu kobciyaa raasamaal Camp ee Kaydadka unugyada, hoos u awooda unugyada muruqa siman qandaraas, yaraynta xaddiga udhigo calcium free, taas oo u haajiraan iyada oo xuubka unug.

Lagu calaameeyey dhawaaqaa vasodilating dhaweynta saamayn "teopeka" diyaarinta (300 mg). Tilmaamaha loogu isticmaalo qeexayaa hantida sida saamayn ah oo ku saabsan xididdada dhiigga durugsan. Theophylline kordhiyaa socodka dhiigga iyada oo loo marayo nidaamka kelyaha, kor u nasashada marinnada muruqa iyo dhiig siman bronki. Sidoo kale, tallaabada of qayb firfircoon waxa lagu gartaa sida lagu durayo fudud. Theophylline ka hortagtaa sii daayo walxaha gudaha iyo dibedda, oo iska xanaajin jawaab xaasaasi ah iyo sidoo kale waxay kordhisaa xasiloonida ee xuubka unug daqal. Haddii hypokalemia bukaanka walax firfircoon sii xoogeysanayo hawo.

Theophylline caawisaa caadi shaqaynaya ee neefsashada, kaakicin xarunta u dhigma ee maskaxda, taasoo keentay in robab ah oxygen dhiig ka wanaagsan, waxa hoos u fiirsashada of carbon dioxide. Drug "teopeka" wuxuu kobciyaa diaphragm ka, taasoo keentay in ay ka gooyay. Waxa kale oo ay kordhisaa qiimaha tilmaame hawsha ansixin mucociliary sii xoogeysanayo murqaha neefsashada iyo intercostal.

Theophylline keenaysaa in mikrotsirkullyatsiyu dhiigga caadiga ah yaraynaysaa formation thrombus, cabudhibayo gaar factor iyo meesha xulkii unugyada dhiig xinjirowga. daroogada sidoo kale hagaajinaysaa socodka tayada dhiigga, waxay kordhisaa caabiga deforming arrimo erythrocytes.

"Teopeka" (300 mg), taasoo cadaadiska guud ee wareegga pulmonary, iyo sidoo kale yareyneysa iska caabin ah ee nidaamka vascular ee sambabada. Sidaas darteed, waa ohyahay ee integuments maqaarka, kelyaha iyo maskaxda hoos. Sidaas darteed la helo theophylline calaamadeeyay kicinta ah ee socodka dhiigga wadnaha, kordhay dhaqdhaqaaqa wadnaha, korodhka unugyada cajiib ah myocardial u baahan tahay ogsijiin, nooleeyaa garaaca wadnaha, xoogga foosha wadnaha oo kaca.

Pharmacokinetics iyo pharmacodynamics daroogada

Ka dib markii bukaanka qaaday kiniinka la theophylline, walaxda si buuxda u nuugo ka soo mareenka caloosha iyo mindhicirka. Cuntada cabniinka saamayn ku heerka of nuugista of daroogada, laakiin heerka uu nuugista iyo ansixin isma badelin. Tan iyo protein plasma xidhana 40% oo ah walaxda firfircoon. Dheef-Theophylline dhacdaa beerka by P450 cytochrome.

Digo ee metabolites soo saaray qaab firfircoon via kelyaha, laakiin 10% ka mid ah daroogada la hareen ee Qaabkiisu. Dhawr arrimood oo saamayn weyn ku-shiid ee theophylline. Sigaarka, qaadashada daawooyinka qaarkood, caadooyinka cuntada, comorbidities, da'da, awoodna u leh in ay hagaajin sarrifka oo ah walaxda firfircoon ee jirka aadanaha. Yaraynta ansixin ee theophylline lagu arkay barar sambabada, cudurka beerka, COPD, iyo wadnaha oo shaqadiisa gaba.

Yaa soo dhaweyn kartaa qalab this?

Waxaa jira xaalado gaar ah oo ah "teopeka" (300 mg). Tilmaamaha loogu isticmaalo qeexayaa cudurada soo socda:

• boronkiitada obstructive qaab raaga,
• seexdaan xibin gal,
• emphysema;
• neefta,
• hypertension pulmonary;
• wadnaha sambabada.

Sidoo kale, daroogada "teopeka" ra'yi-celin wanaagsan oo lagu saleyn karaa in lala daroogooyinka kale ee daaweynta dabiiciga ah kelyaha bararka. Bukaan-socodka ogow oolnimada sare oo qalab iyo dhoweynayo for daawaynta cudurada of nidaamka neef-mareenka.

sababo

Si kastaba ha ahaatee, daroogada waxaa loo isticmaali karaa qof kasta oo aan, sababta oo ah joogitaanka of tiro ka mid ah digniin ka lacagtaas. sababo "Teopeka" waa sida soo socota:

• dhiigbaxa nooca stroke,
• qalalka,
• dhiigbaxa mareenka caloosha iyo mindhicirka ee taariikhda,
• formation boog in xubnaha dheefshiidka,
• severities sare tachycardia;
• hypertension ama hypotension;
• diidmo,
• gastritis, Ulasocto aysidhka sare;
• Carruurta da'doodu tahay ilaa 12 sano.

In joogitaanka ugu yaraan mid ka mid ah syndromes ama shuruudaha theophylline daroogada ka tanaasulaan waa in

waxyeellooyin

Waxaa jira arrin koox weyn oo dhinaca saamaynta ka qaadato "teopeka" diyaarinta (300 mg). Tilmaamaha loogu isticmaalo saamiyada ay ku daliilka systemic:

• cudurada of habka dareemayaasha: madax xanuun, wareer, rabshooyin hurdo, nasasho la'aan, welwel iyo caro kordhay, gariir,
• cillad ka mid ah wadnaha iyo xididada dhiiga: tachycardia, arrhythmia, hypotension, kaadida oo soo badata weeraro angina, angina been ah;
• xadgudub iyo mindhicirka hawlaha caadiga ah: lallabo, gastralgia, matag, laab, reflux, boogaha sii daridda, shuban, hoos rabitaanka cuntada,
• daliilka cadaanyo: finan maqaarka ah, qandho, cuncun,
• ka mid ah dhacdooyinka kale ee loo kasin ka qaadashada daroogada ayaa xusay: tachypnea, albuminuria, diuresis kordhay, xanuun sternum, hematuria, bafinayo, dhidid kordhay, gipoglekemiya ah.

Sida caadiga ah, edbinta qiyaasta yaraadaan waxyeelo waa la dhimay ama dareerka dhammaantiis.

Sida loo qaato daawada?

Waxaa loola jeedaa ka boronkiitada, sida "teopeka" loo qoondeeyay kaliya uu dhakhtarka xaadirka ah iyo qiyaasta la doorto shakhsiga ku saleysan. The nome maalin kasta celcelis ahaan u dhiganta 400 theophylline mg. Haddii bukaanka si fiican u xanbaarsan yahay daroogada, ka dibna 2-3 maalmood ka marka ugu horeeysa ee daawada ka dib, mugga kordhay 25% oo dheeraad ah by ikhtiyaar dhakhtarka.

Marka la helo hab ka boronkiitada "teopeka" in dose maalinle ah oo ka yar 900 mg gacanta content theophylline muhiim ma aha in dhiigga qofka bukaanka ah. Haddii aad u hubiso muujinta sarkhaan, ee u baahan in la dhiso gacanta heerka fiirsashada of qayb weyn ee firfircoon ee dhiigga. Best tilmaamayaasha loo arkaa 10-20 micrograms per ml. Haddii content theophylline dhiigga qofka bukaanka ah ee uu ka badan yahay sida caadiga ah, horumarinta dhawraan falcelin xun. Xaaladdan oo kale waxaa lagama maarmaan ah si loo yareeyo qiyaasta of daroogada, iyo saamayn-ku-daweyn wiiqi doonto.

waxaa jiri kara badinta?

Bronchodilators sida "teopeka" keeni karaan xanuunada daran ee jirka haddii ay dhacdo badinta. Marka si sax ah u dhigmaan heerka maalin kasta oo ka mid ah hab la helo oo ka mid ah calaamadaha soo socda soo bixi kara:

• hoos rabitaanka cuntada,
• hurdo la'aan,
• shuban;
• qaabka garaaca ventricular;
• tachycardia;
• dhiig ee nidaamka dheefshiidka,
• tachypnea;
• gariirka,
• walaaca,
• barrar maqaarka ;
• kor u kacay excitability;
• cabsi iftiimaa,
• matag dhiig.

Waxa kale oo ay u horumariyaan karaan sumayn daran, taas oo u muuqato in calaamadaha soo socda:

• dhacdo of suuxdintu;
• hypokalemia;
• kelyaha, myoglobinuria;
• hypotension;
• wareer;
• hyperglycemia;
• aysiidh dheefshiidka.

Maxaa la sameeyaa haddii ay taasi?

Haddii ay jirto caddeyn ah calaamadaha ama looga shakisan yahay iyaga ka mid ah waxay u baahan yihiin si ay u sameeyaan lavage a gastric, siiyo chelators bukaanka, caloosha jilciya, daroogada, iyo sidoo kale abaabuli diuresis plasmasorption, kelyaha iyo hemosorption. Haddii bukaanka qabo qalal, ka dibna waxaa lagu talinayaa in ay bilaabaan daweynta oksijiinta iyo xididka "Diazepam" kuwaas oo caawin doona in ay si wax ku ool qabtaan qabashada. In the case of lalabo iyo matag waa in loo magacaabo daawooyinka xididka "Ondansetron" iyo "Metaklopromida" dhawaaqaa.

Waa maxay daawooyinka aan la isku daro "teopeka" karaa?

Bronchodilators sida "teopeka 'waa in aan wada qaado macrolide-antibiotic ah" Allopurinol "," cimetidine "," Lincomycin "," isoprenaline ", iyo sidoo kale-piller sababtoo ah daawooyinkan caawin yareeyo ansixin ee theophylline.

Waxaa laguma talinayo in la isu geeyo qaadashada of beta-blockers, gaar ahaan kuwa aan la xushay, iyadoo "teopeka" daroogada, kaas oo laga yaabaa in Cidhiidh bronki iyo saamaynta bronchodilator hoos u of theophylline ah.

Haddii "teopeka" wada codsatay la "Furosemide" caffeine iyo walxaha kale oo kicin beta-2 receptors adrenergic, waxqabad ee ay ka kooban aasaasiga ah waxaa aad u kordhay. Haddii la theophylline "Aminoglutitemidom" marka la isku daro, wax ugu horeysay ee uu bilaabo inuu si firfircoon u raaca jidhka iyo dhibicyo hufnaan ay ka.

"Acyclovir" waa awoodaa in la kordhiyo fiirsashada of firfircoon "teopeka" ugu weyn iyo kordhisaa saamaynta xun ee ay soo dhaweynta. ifafaale la mid ah ayaa lagu arkay markii co-maamula daawooyin theophylline "Dialteazem", "Felodipine" "Verapamil", "Nefedipin". daawo ma beddeli saamayn bronchodilator ah, si kastaba ha ahaatee, bukaanka waxaa laga yaabaa in ay la kulmaan astaamaha dhibaato ama badinta.

Maandooriyaha "Disulfiram" awood sii kordhaysa dhiig theophylline in tilmaamayaasha muhiimka ah nabar sunta halista ah. "Propranolol", in la barbardhigo, yaraynaysaa "teopeka" oggalaansho oo ah walaxda firfircoon. Fiirsashada of theophylline waxaa kordhay somestnom ay soo dhaweynta leh "enoxacin" iyo fluoroquinolones. Marka therapy theophylline hoos ku oolnimada of lithium cusbada.

Haddii la isku daro daawaynta "pentobarbital", "carbamazepine", "Isoniazid", "rifamycins", "sulfinpyrazone" oggalaansho kordhay "teopeka" iyo yaraynaysaa ah waxtarkeeda. Marka concomitantly la theophylline "phenytoin" waxaa jira Iscelin ay labada dhinac ka kooban firfircoon ee dhiigga qofka bukaanka ah.

Xeerarkani waxay si gaar ah muhiim, iska indha-tiray iyaga waa ben leh dhibaatooyin caafimaad. Sidaa darteed, ka hor inta aysan "teopeka", si taxadar leh u akhri tilmaamaha. Oo haddii lagugu daweynayo for mid ka mid ah daawooyinka ku xusan, la tasho dhakhtarkaaga.

Sidee si ay u iibsadaan daawada iyo sida daroogada ah oo qiimihiisu yahay?

In view of the sababo halis ah oo waxyeelo of this daroogada, "teopeka" daayay farmasiyada oo keliya by qoro.

Drug "teopeka" Qiimaha waa celceliska in Russia waa 160 rubles, bandhigay farmasiyada by saarayaasha kala duwan. Mid ka mid ah noocyada - daawo for "Borschagovsky CPP SPC" shirkadaha dawooyinka ee Ukraine. Its qiimaha waa 155 rubles. wax soo saarka Ruush ah "teopeka" daroogada, 300 mg waxaa lagu fuliyaa ee shirkadaha of JSC "ganacsi Pharmaceutical" iyo "Valens". daawooyinkan ku kacaysaa 290 rubles iyo 190 rubles siday u kala horreeyaan.

Guud ahaan, "teopeka" daroogada, qiimaha la aqbali karo, loo arkaa daawo la awoodi waayo, qaar badan muwaadiniinta. In la barbardhigo dhigooda Yurub qalab this waa wax badan ka jaban. wax soo saarka Ruush ah "teopeka" daroogada ka dhigtay in ay la awoodi karo.

Digi markii qaadashada daawooyinka

Marka la helo "teopeka" daroogada, dib u eegista ah oo fiican, waa in aad bixiso macluumaadka soo socda fiiro. Haddii bukaanku leeyahay kaafi wadnaha ama wadnaha, atherosclerosis, cardiomyopathy, boog caloosha iyo mindhicirka, cudurka beerka, kansarka qanjirka 'prostate', reflux pipe, uurka, hypothyroidism ama ka dhaxleen kor u qalal, theophylline daroogada waa in la qaato si taxadir leh.

Carruurta ka yar 12 sano iyo bukaanka ka weyn "teopeka" dhif ah loo magacaabay.

Waxaa laga yaabaa in isticmaalka noocyada malawadka of daroogada, laakiin ay tahay in la si taxadir loo isticmaalo heley malawadka iyo shuban syndrome ah. Bukaanka qaba qabatinka in dhibic sigaarka hoos saamayn daaweynta "teopeka".

Waxaa loo tixgeliyaa theophylline iyo xanthine taagayo daaweyn wadajir ah aan la'ogolaan karin. Haddii bukaanka waxaa dadka waayeelka ah ayaa sheegay in cudurrada saameen, caabuq fayras, cudurka beerka, wadnaha iyo xididada dhiiga, dhakhtarku waa lagama maarmaan in la saxo dose oo ah dawada.

Ma qaadan karaa daroogada ah haweenka uurka leh?

Qof dumar ah oo uur leh medicament waxa lagu tilmaamayaa joogitaanka of tilmaamo daran tan theophylline waa ay awoodaan in ay dhex gasho mandheerta. Haddii dhaweynta "teopeka" waxay muujinaysaa wax Nuujisa, nuujinta waa in la joojiyo.

Buugani waa qayb aad soo fududeeyay oo ka mid ah tilmaamaha dhameystiran, kaas oo ku lifaaqan daroogada "teopeka". Waa in la taxadir leh u akhri ka hor inta la isticmaalayo. Haddii ay jirto wax aad tahay wareersan ama shaki, la tasho dhakhtarkaaga.