Daawada "Avastin": Kurtumm

The daroogada "Avastin" waa qalab casri ah soo wajahay cudurka kansarka. Waxaa loo isticmaalaa in lagu daaweeyo noocyo kala duwan oo kansarka, waxay ka caawisaa si loo xakameeyo muuqaalka kore ee metastasis, yareeyo permeability microvascular iyo joojiyo horumarka cudurka. Maalmahan, dad badan, dadka qaba kansarka lagu daaweeyo daaweyn daroogada "Avastin". Reviews ku saabsan way kala duwan yihiin. Waxaa jira tusaalooyin ka mid ah dhaqdhaqaaqa wanaagsan ee daawaynta cudurada iyo dib u eegis badan oo ku saabsan tarayn ee daroogada. Qaar ka mid ah dadka "Avastin" sababa waxyeelo halis ah.

Qaab-dhismeedka

The qayb "Avastin" firfircoon ugu weyn - bevacizumab. Daawada waxaa iibin sidii shancosbitaal ah, taas oo laga sameeyey oo xal u galiyey xididka. "Avastin" waa midab ama uu leeyahay midab khafiif ah brown. Sales waxaa laga heli karaa laba nooc oo ah "Avastin" kala duwan ee fiirsashada of qayb weyn ee firfircoon: 100 mg / 4 ml iyo 400 mg / 16 ml.

maragga

Daawada waxaa la tilmaamay ee cudurada soo socda:

• Kansarka naasaha ku jira marxaladaha dambe markii metastasis bilaabo.
• carcinoma cell kelyaha.
• kansarka mindhicirka.
• kansarka sanbabada ee unugyada Non-yar.
• Glioblastoma (noq).
• Age la xiriira xumaanshaha macular (AMD), meesha ay buradu ku okolomakulyarnoy, rinopatiya diabetic.
• Currently, waxaa Muqdsho isticmaalka "Avastin" ee indhaha. Reviews for daawaynta cudurada indhaha la xidhiidha koritaanka bahal vascular, positive.

sababo

Iyadoo la tixraacayo tilmaamaha si daroogada waa in aan la isticmaali "Avastin" in kiisaska noocaas ah:

• In jiritaanka dareenka sii kordhaya ee bukaanka in mid ka mid ah qaybaha ku jira diyaarinta.
• Inta lagu guda jiro uurka iyo nuujinta. Studies on saamayn "Avastin" ee this category ka mid ah bukaannada ayaa lagu sameeyay. Waxaa la og yahay in walax daroogada gelin mandheerta, taas oo keeni karta in xakamaynta ilmaha caloosha ku angiogenesis. Dumarka jira da'da dhalmada, waxaa lagu talinayaa in la isticmaalo ka hortagga uurka lagu kalsoonaan karo ugu yaraan muddo lix bilood daaweyn daroogada this ka dib. Intaa waxaa dheer, haddii loo baahdo, "therapy Avastin" talinayaa joojinta ee naas-nuujinta, sida ay sababi kartaa koritaanka iyo horumarka ee dhashay. Si kastaba ha ahaatee, cilmi aan la xaqiijiyay.
• da'da Carruurta.
• In kelyaha iyo beerka. Studies of saamaynta daroogada for this category ka mid ah bukaanada la sameeyay.

dhibaato

Bukaanjiifka qaar waxyeelo marka daaweyn la siiyay "Avastin". Reviews soo jeedinaya in jawaabta si daroogada noqon karaan kuwo halis ah:

• Dalool of mareenka caloosha iyo mindhicirka.
• Hemorrhage, ee Vol. H. sambabada.
• thromboembolism halbowle.

Sidoo kale wuxuu ka kooban yahay waxyeelooyin kale oo si "Avastin" Buuggan daroogada edbinta. Reviews iyaga ka mid ah marar badan waxaa lagu arki karaa. Waxay kala yihiin:

• Kororka cadaadiska dhiigga.
• Xaaladan oo ah xanuunka iyo bararka ee caloosha.
• Dareen ah daciifnimo.
• Asthenia.
• Heart failure.
• Neutropenia, leukopenia, anemia.
• Keeni lallabo, matag, stomatitis.
• Horumarinta ee anorexia.
• dhiigbaxa dabada.
• Hypoxia.
• ileus.
• Rhinitt, dyspnea.
• Maqaarka midabka noqdo qalalan iyo isbedelka.
• aragga.
• Tabar ee muruqyada.
• Horumarinta ee cudurada kaadi-mareenka.
• Waxa uu kordhiyaa heerkulka jidhka.
• Xanuun, isagoo deegaamaynta kala duwan.
• Sepsis - caabuqa ee jirka.
• heerka Hemoglobin waa la dhimay.

ganaaxyada

Marka daaweynta daawada "Avastin" iyo dhamaadka codsiga for a dheeraad ah muddo lix bilood ah waxaa lagu talinayaa in la isticmaalo ka hortagga uurka. Isticmaal of daroogada, iyo sidoo kale go'aaminta ay qiyaasta ka dhigi karaa oo keliya ku takhasusay khibrad leh. Daawada waa in aynan xal dextrose.

codsiga

Diyaarinta "Avastin" waxaa soo bandhigay oo keliya / faleebo, maamulka / jet mamnuuc. qiyaasta waxay ku xiran tahay nooca cudurka. Solution "Avastin" waa in la sameeyaa xaaladaha dhalaysnimo badnaan kaliya ka yar. qiyaasta loo baahan yahay "Avastin" milo in 100 ml oo ah sodium chloride xal 0.9% (bukaanka qaba miisaanka weyn guud ahaan waa in ay gaaraan 200-250 ml).

faleebo ugu horreeya ee "Avastin" waa in ay 90 daqiiqo. Codso alaabta soo socota ka dib markii chemotherapy. Haddii ay timid ka dib markii maamulka ugu horeysay, ka galiyey markii labaad waxaa la samayn karaa 60 daqiiqadood, oo mar saddexaad - 30 daqiiqo. Haddii aad leedahay waxyeelo, horumarinta aan kula taliyay in la yareeyo qiyaasta of daroogada. Haddii aad u baahan tahay in, ka dibna waxaad u baahan tahay si ay u joojiyaan daaweynta "Avastin" waqti qaar ka mid ah ama u wada joojiso.

badinta

Marka uu u xilsaarayo "Avastin" at qiyaasta ugu badan (20 mg / kg miisaankiisa jirka, jirkaaga 2 todobaad bareeg) ayaa dhici kara in bukaanka calaamadaha xad dhaafka ah. Bukaanleyda qaarkood waxaa jiray joog- dhafoor-xanuun daran. sii xumayn karto calaamadaha waxyeelo.

xaaladaha kaydinta

heerkulka kaydinta daawada waa 2-8 degrees Celsius. nolosha shelf - ilaa 24 saacadood. "Avastin" ma karaan ama rux. Xalka kuma jiraan sheyga, sidaa darteed haddii ay tahay, waa in la wada baabbi'iyey.

dhibcood muranka: ka dib u eegista togan iyo kuwa taban oo ku saabsan daroogada. Iyamaad doonaysaan in ay aaminsan yihiin?

The daroogada "Avastin", dib u eegista ah oo waxaa jira wax wanaagsan iyo wax xun gabi ahaanba, iyadoo sanad walba maraya iyo aad u badan inta badan qoray dhakhtarku. Cilmi ahaan la xaqiijiyey waxtarka caafimaad oo lagu daaweeyo noocyo badan oo kansar ah.

Xukun waxtarka daawaynta bukaanka macluumaad ku saabsan daaweynta daawada "Avastin" ka heli kartaa. Reviews bukaanka qaadato aragti dhaw on.

daroogada waxa uu leeyahay qiimo sare oo ku filan. Celcelis ahaan, waxay ku bilaabataa 15 kun. Xoq. Sidaa darteed, marka bukaanka qaba cudurro halis ah soo food saaray dhakhtarka daaweynta daroogada, waxay isla markiiba bilaabaan inay baadhaan wixii macluumaad ah ee ku saabsan daroogada "Avastin" Kurtumm bukaanka, codsanaya this daroogada, iyo sidoo kale tilmaamaha on isticmaalkeeda.

Inta badan aad macluumaad ku saabsan sharci darro ah daaweynta "Avastin" Marar aad u daran ka heli kartaa. Waa in aynaan illoobin in aanay had iyo jeer dhakhtarku kuu qoro daawo, si taxadar leh loo qiimeeyo oo dhan Gudigga in oo diyaariya in ay daroogada "Avastin" edbinta. Reviews ku saabsan saamaynta togan ee daroogada ee kiisaskan - ifafaale dhif ah. Waxaa lagama maarmaan ah in ay u digtoon in ay caafimaad, iyo in la xasuusto in daawaynta cudurada halis ah sida kansarka, waa in la sameeyaa oo keliya shaqaale u qalma.

In xaaladda kasta, waxaa jira sababo badan oo "Avastin" aan loo dhowaan karin, bukaanka iyo fududeeyo koorsada cudurka. Sidaas waxaad u baahan tahay in aad ka fikirto ujeeddo leedahay iyo in aan la uun u Hanuunay by the dib u eegista xun.

Ka fiirso qaar ka mid ah views daaweynta la daroogada this.

Reviews ku saabsan "Avastin" daroogada

Sida kor ku xusan, ka dib u eegista ah ee wax soo saarka this daawooyinka waa mid aad u diidani. Si kastaba ha ahaatee, dad badan oo buka sheegaan in daaweynta cudurka muuqataa horumar badan. In qaar ka mid ah waxaa jira hoos u dhac ku size buro. Laakiin, nasiib daro, waa in aan la filayaa in soo kabashada buuxda. "Avastin" waa ay awoodaan oo keliya in la kordhiyo nolosha bukaanka oo aad u raaxo badan.

Waxaa lagu tilmaamay badan oo xaaladood oo waxyeelo. The xoojinta inta badan lagu arkay madax xanuun, cadaadis dhiig oo korodha. Cirbadaha "Avastin" indhaha dadka bukaanka ah qaar ka mid ah in ay keeni lumis arag iyo xataa indho la'aan.

In Maraykanka, waxaa jiray isku xigta halis ah in ka badan isticmaalka "Avastin" oo lagu daweeyo xumaanshaha macular. Duray sida daroogada galay hallawda oo keentay inay go'an dhamaystiran oo waxyeelo. Isla mar ahaantaana, 16 bukaan ayaa la galay cudurada bu'da halis ah. Qaar ka mid ah horumariyo indho buuxda. Laakiin "Avastin" sii wadaan in ay isticmaalaan labada Maraykanka iyo Europe. isticmaalka noocan oo kale ah baahsan ee daroogada ma aha markhaatiga kor saaran aan la xidhiidha horumarinta sharci-darro ah, iyo kharashka yar ee daawada la "Lucentis" sharci ah, oggolaaday ee daaweynta ee xumaanshaha macular marka la barbar dhigo.

Farqiga qiimaha daroogada waa badan. Iyadoo dalka Maraykanka qiimaha "Avastin" waa $ 50, qiimaha "Lucentis" - 2000 doolar. Ogsoonow in ka barta of view of muuqaalka kore ee dhibaatooyinka iyo saameynta dhinaca, iyo sidoo kale horumarinta endophthalmitis "Lucentis" Ma aha mid wanaagsan. Taasi waa sababta dad badan ayaa halis ugu jira iyo iibsan ah "Avastin" aan rasmi ahayn.

Sida laga soo xigtay dhakhaatiir badan, farsamo duro dhibic oo dhan waxay ka dhigan tahay. Research waxaa loo baahan yahay in meesha this. Qaar ka mid ah iyaga ka mid ah ayaa horey u sheegay. Sidaas darteed, marka la barbar dhigo falalka bevacizumab iyo ranibizumab (Walxaha firfircooni "Avastin" iyo "Lucentis", siday u kala horreeyaan). Waxaa jiray meel laba waxbarashada, laakiin natiijada ayaa ku muransan yahay, maxaa yeelay, inta lagu guda jiro ugu horeeyay ee u soo baxay inay noqon ammaan, bevacizumab, iyo tan labaad - ranibizumab.

Si aad u taariikhda, Russia mamnuucay daroogada loo isticmaalo indhaha. Laakiin weli waxaad ka heli kartaa iibiyaha iyo dhakhtar ku samayn doonaa irbad. Dhakhaatiirta Indhaha door bidaan ah "Avastin" aan qaali ahayn, sida in guriga daawo-commerce ayaa sii baahaya. Ka dib oo dhan, in ay soo jiidan doonaan dareenka bukaan-socodka u fursadaha ka jaban inta badan ka sahlan.

Xaaladdan oo kale, waa in la ogaadaa in bukaan badan oo la AMD waxay ahaayeen horumar weyn ka dib markii ay ka dhigtay shots, "Avastin" isha. Reviews oo ka mid ah dhaqdhaqaaqa daawaynta waa wanaagsan. In yar irbadaha daroogada ka Xasishay barar indhaha, waxaa jiray horumar ku toosan muuqaal ah. Therapy leedahay saamayn togan ma isla markiiba, laakiin ka dib markii waxyeelo ka dhacaan. Sidoo kale, ka filan saamayn muuqata wanaagsan ka dib markii la isku duro ugu horeysay ee daroogada si buuxda aan micno lahayn.

"Avastin" + chemotherapy: dib u eegista, daaweynta

Marka la barbardhigo ah dib u eegista khilaafsan oo ku saabsan isticmaalka daroogada ee indhaha, diraasado ah ayaa muujiyay waxtarka "Avastin" isku dhafan oo chemotherapy ee lagu daaweeyo kansarka mindhicirka. In codsiga ah ee daawada chemotherapy caadiga ah "Avastin" caawiyaa yareeyo size of burooyinka mindhicirka. Intaas waxaa sii dheer, natiijooyinkii therapy this ee ka lumay ee metastases beerka in 78% bukaannada. Sidaas darteed, oo ku saabsan saddex-meelood meel ka mid ah bukaannada ay awoodaan in ay u fuliyaan qalliinka, taas oo hoos xaalad wanaagsan badbaadin karin noloshooda.

Sidoo kale, daraasada ayaa lagu ogaaday in "Avastin" waa sida wax ku ool ah oo loogu talogalay bukaanka dadka waayeelka ah sida in bukaanka ka yar.

Codsiga waxaa si wadajir ah ula capecitabine daroogada kordhisaa rajada nolosha bukaannada qaba kansarka mindhicirka, waayo, saddex ilaa shan sano.

Waxay kaloo ka caawisaa in la kordhiyo nolosha iyo in la yareeyo formation of metastases in kansarka naasaha iyo kansarka sanbabada ee unugyada yar yahay isku-dar ah "Avastin" + chemotherapy. Reviews daaweynta sida fiican. Si kastaba ha ahaatee, xaaladda ay tahay mid la mid ah, suurtagalnimada soo kabashada buuxda waa ay yar tahay.

oggolyahay clinical

• Kansarka mindhicirka - la co-therapy "Avastin" la IFL (irinotecan, fluorouracil, leucovorin) fidiyaa badbaadada ku dhowaad 5 bilood. Isticmaalka "Avastin" oo ay la socdaan chemotherapy kordhin kartaa cimri by qiyaastii 4 bilood.
• kansarka naasaha xadka-. Infusions "Avastin" 10 mg / kg dura laba toddobaad si wadajir ah ula paclitaxel si weyn u kordhiyo suuragalnimada in la hakiyo horumarinta cudurka. daaweynta noocan oo kale ah ee jeer hagaajinaysaa saamayn chemotherapy.
• kansarka sanbabada ee unugyada Non-yar. Daaweynta "Avastin" si wadajir ah ula chemotherapy (taas oo daroogada platina ku salaysan) waxay kordhisaa suurtagalnimada ee badbaadada iyo kordhiyo cimriga.
• carcinoma cell kelyaha. Isticmaal "Avastin" si wadajir ah ula interferon Alfa-2a dheeraada muddada jiritaanka marka loo eego la isticmaalayo kaliya interferon Alfa-2a.
• Marxaladda afaraad ee Gliom malignant. Ka dib markii ay pre-radiotherapy daaweynta "Avastin" dheerayn karaan nolosha ku dhowaad lix bilood.

Sidaas darteed, "Avastin" waa daawo casri ah oo lagu daweeyo burooyinka kala duwan. Saamaynta daroogada aan la si buuxda u baarayaa. Si kastaba ha ahaatee, waxaa sii kordheysa qoray by dhakhaatiirta daaweynta noocyada kala duwan ee kansarka.

Codsatay "Avastin" ee indhaha, halkaas oo waxa uu siiyaa saamayn ugu dhawaaqaa wanaagsan ee daaweynta ee AMD. Daawada waa wax qaali ah, sidoo kale keeni kartaa waxyeelo badan. -celin Guud ahaan ka dib markii la isticmaalayo "Avastin" waa positive, laakiin waxaa jira diidmo ah.

Bukaanka qaar ka mid ah, "Avastin" waxa uu ahaa gabi ahaanba aan waxtar lahayn, iyo qaar ka mid ah keenaan waxyeelo halis ah. Sidaa darteed, daroogada waa in loo magacaabo oo keliya qof takhtar ah oo aqoon leh, la tixgelin waajib ku ah oo dhan ay suurtagal tahay jawaab bukaan gaar ahaaneed si ay qaybaha daroogada. Intaas waxaa sii dheer, galiyey waa in la sameeyaa hoos jira xaalad sterile. Cancer - cudur halis ah oo keeni kara dhimasho. Isticmaalka "Avastin" daroogada ma siin damaanad sixun daawo ah, laakiin waxa ay joojin karaan horumarka cudurka iyo dheeraan nolosha bukaanka. Oo dadka qaba cudurada dilaa waxay leeyihiin heshiis weyn!