Beta-blockers

Beta-blockers waxaa loo isticmaalaa sida daawooyinka antihypertensive tan iyo demoqaraadiyad hore. Tan iyo markii la ogaado oo ka mid ah natiijooyinkii hore ee daaweynta iyo taariikhda ay ku oolnimada waxaa si wanaagsan loo diiwaangeliyaa ee cilmiga badan ay gacanta ku hayso, iyo sidoo kale marka la barbardhigo saameynta hab casri ah oo dheeraad ah.

Beta-blockers waxaa si guul leh loo isticmaalo si loo yareeyo cadaadiska dhiigga iyo in laga hortago horumarinta cudurka wadnaha iyo dhimashada. hab ay of ay tallaabo antihypertensive ku salaysan yahay dhimista ee wax soo saarka wadnaha ay sabab u tahay hoos u dhac ah oo xoog iyo inta jeer ee foosha. Intaa waxaa dheer, beta-blockers gacan ka xakamaynta of dheecaan of renin in juxtaglomerular (okoloklubochkovom) qalab kelyaha iyo in arrintan la xiriira, si wax ku ool ah loo xakameeyo dhaqdhaqaaqa reer renin-angiotenzinaldosteronovoy iyo nidaamyada vasomotor dhexe.

Isticmaalka daba dheeraaday ka cadhaysiinina karaa hoos u dhac caabin vascular (total durugsan), maadaama ay sii kordhayeen dareen baroreceptor iyo wax soo saarka ee derbiga vascular of prostacyclin (vasodilating prostaglandin).

Kala duwan beta-blockers loo isticmaalo qaabab u dhigma, waxay leeyihiin saamayn isku mid ah hypotensive. saamaynta antihypertensive Full uu yeesho laba ilaa afar toddobaad gudahood. "Tirtiridda" syndrome laga yaabaa inuu dhaco ka dhanka ah asalka ah ee daaweynta mudada dheer. Wixii ka hortagga daroogada isla markiiba aan la joojin, iyo si tartiib tartiib ah loo yareeyo qiyaasta toban toban maalmood.

gaadhista systemic daroogada, gaar ahaan kuwa aan la xushay, ka cadhaysiinina karaan horumarinta waxyeelo wadnaha iyo noncardiac Caafimaad ahaan la taaban karo.

Kooxdu waxay ugu horeysay waxaa ka mid ah xanuunada ee asalka psycho-niyadeed (niyad-jabka, hurdo xumo, iwm), calaamadaha neef mareenka (bronchospasm), vasoconstriction durugsan (claudication go'aysa, jirka qabow, iwm), tabar-dari muruq, kacsi la'aanta. waxyeelo Extracardiac wakiil dhantaalan ee function kelyaha sababa socodka dhiigga hoos kelyaha, dhibaatooyin la egyahay iyo shiid carbohydrate.

In daliilka wadnaha group ka mid ah:

• wadnaha jebinta function shubto la socda oo leh calaamado of deficiency;
• Go'doominta (sinoatrialnaya atrioventricular) wadnaha iyo bradycardia;
• hypotension ka dhanka ah hoos u dhac xad-dhaafka ah ee dhiig-karka,
• saamayn antiarrhythmic.

Waa in la ogaadaa in noocyo kala duwan oo guryaha pharmacological xanibaha kuu ogolaanaya inaad si loo doorto daawada fiicnayn kasta kiiska. Tani waxay qaadanaysaa xisaab iyo tolerability ee daaweynta, khatarta ugu yar ee dhacdooyinkan gurracan, mudada soo-gaadhista iyo nooca xaaladda caafimaad oo galay.

Magacaabidda beta-blockers sida therapy keli ah u oggolaanaysa in caadi ah ee cadaadiska dhiigga ee ku saabsan 40-50% bukaannada qaba dhiig-karka. In la barbardhigo saamaynta on bukaanada da 'yar, dhexe iyo wixii ka weyn, saamayn waa mid yara hooseeya ee dadka waayeelka ah. Isticmaalka diuretics thiazide isku dhafan oo ah beta-xanibaha tiraa kala duwan. Sidaas darteed, wax ku oolnimada therapy isku dhafan oo noocan oo kale ah waxay kordhisaa in 78-80%.

Beta-blockers in lagu daweeyo angina mashquulin meel gaar ah. In cudurkan, daawooyin sida waxaa loo isticmaalaa sida Anaprillin (obzidan), Sotalol, Atenolol, Konkor, Monotard.

Saamaynta ay dhammaan daawooyinka, kuwaas oo loogu talagalay in lagu yareeyo cadaadiska dhiigga iyo "deceleration" garaaca wadnaha. qiyaasta daawada iyo wixii waa in la soo xulay dhakhtar Gaarna shakhsi.

Maandooriyaha yihiin in neefta, cudurada sambabada obstructive chronic, block atrioventricular labaad ama darajada saddexaad. Aan lagula talinayaa isticmaalka beta-blockers in dulqaad glucose oo yaraada, cudurka halbowlaha durugsan, ciyaartoyda iyo shakhsiyaadka firfircoon jir ahaan.