Kordhinta prolactin: sababaha, calaamadaha, daaweynta, cawaaqibka

Haddii Qolol prolactin hormone, caadada u dhibtay iyo dheelitirka hormoon, oo halkaas waa dhalmo la'aan ama dhibaatooyin siday ilmo. Sidaa darteed, haweenka waxay u baahan yihiin si loo ogaado at its heer ee dhiigga inta lagu jiro qorshaynta uurka.

Prolactin waxaa soo saaray qanjirka pituitary ee - qanjirka hormoonada jidhka ku yaalla maskaxda. Hypothalamus gacanta ku habka this. heerka hormoonka waa mid aad u xasaasi u ah arrimo dibadeed. Sidaas daraaddeed, prolactin sare waxaa laga yaabaa in sababahan soo socda:

• daroogada;

• renal failure;

• stress,

• cirrhosis,

• seexan,

• Cushing ee syndrome,

• Cudurka Addison ee ;

• Acromegaly;

• sarcoidosis;

• neyrotuberkulez;

• barar,

• muddada dhalmada;

• uurka;

• Carbinta ibta naaska,

• naas-nuujinta,

• galmada;

• suuxdinta,

• dhaawac iyo qaliin xabadka.

Waqtiyo kala duwan ee wareegga ah ee heerka hoormoonka ee dhiigga ku kala duwan tahay 6 ilaa 28 ng / ml. Si aad u hesho natiijo lagu kalsoonaan karo laguma qaadi karo ka dib markii falanqaynta oo hurdo ah ama nidaamyada. dheecaan ee prolactin dhacdaa pulsed, wajiga inta jeer ee ku tiirsan of wareegga. Waxaa sidoo kale jira isbedbedelka maalin ay heer, tusaale ahaan, ka dib markii tooso fiirsashada hormone yar. Ka dib markii seexan dheecaan kordhay iyo koraa riyo.

Mid ka mid ah saddex-meelood meel dadka bukaanka ah kuwaas oo sare u prolactin, helay adenoma pituitary. Haddii ay size waa weyn yahay, heerka hoormoonka waa in ka badan 100 ng / mL. Heerarka hoose wuxuu ahaan karaa microadenomas ee tirada yar, lama dareemo by X-ray.

The habka ugu wargelin lagu ogaado burooyinka pituitary - MRI ah. Waxaa lagama maarmaan noqotay in qorshaynta ee ilmaha, haddii uu jiro tuhun ah adenoma ah, sida burada weyn oo laga yaabaa in ay gacan dhibaatooyin.

Cabirka microadenomas pituitary aan ka badnayn 1 cm. Oo waxay ku koraan si tartiib ah oo inta badan waa benign. dhexroor Macroadenomas ka badan 1 cm ka weyn. Waxay waxaa weheliya madax xanuun, isbeddel ah ee beeraha la daawado iyo khasaaro mararka qaar dhamaystiran waxaa ka mid ah. Marka macroadenoma ogaado waa wada tashi loo baahan yahay ee qofkale oo a. Waxa uu go'aan ku saabsan qalliinka. Inta lagu guda jiro uurka microadenomas inta badan ma bedesho, laakiin burooyinka of size waaweyn ee 20% ee kiisaska waxaa sii kordhaya.

Prolactin waxaa sidoo kale si joogta ah Qolol in kelyaha (chronic). Marka kelyaha badalida caadi ah oo ay dheecaan.

Haddii prolactin waxaa Qolol, goolka ee daaweynta ee soo socda:

• yareeyo heerka;

• celin wareegga;

• yareeyo size burada, haddii la joogo.

Mid ka mid ah daawooyinka loo isticmaalo in lagu hoos hormone - waa Parlodel, taas oo agonist dopamine ah. Waxa uu hakiyo dheecaan ee prolactin by madadaalo receptors ee maskaxda. Qiyaasta waxay ku xiran tahay darnaanta iyo nooca cudurka. Ka dib markii hordhaca ah ee wareegga bromocriptine waa lay soo celiyey ka dib markii celcelis ahaan 7 todobaad. In kasta oo bukaanka ka mid ah waxay ku dhacdaa dhowr maalmood.

Bromocriptine sida caadiga ah qaadato dhowr jeer maalintii. qiyaasta lagu kordhin karaa haddii loo baahdo. Daaweynta waa in ay dhowr wareegyo ka dib markii dib u soo celinta ee caadada ah si looga hortago soo noq. Dhibaatooyinka ay keento bromocriptine:

• daal,

• wareer;

• madax-xanuun,

• matag,

• afka oo qalala,

• lallabo.

Si loo kordhiyo prolactin keeni kartaa hypothyroidism. Qaadashada Gomonov kiiskan keenaysaa in caadi ay heer.

Tilmaamayaasha for prolactin si ay u falanqeeyaan soo socda:

• osteoporosis;

• gynecomastia;

• awoodba hoose iyo libido;

• hirsutism;

• cayilka;

• boosaska culus;

• xanuunada nuujinta;

• dhalmo la'aan;

• anovulation;

• naaska,

• doorashada ee ibta naaska,

• amenorrhea, oligomenorrhea;

• xanuunka naaska xilliile ah.

Sayidka, prolactin kordhay, in kiisaska intooda badan ay sabab u tahay adenomas pituitary. Intaa waxaa dheer, sababaha caadiga ah ee ay fiirsashada sare waa hypothyroidism. fiirsashada korodhka prolactin keenaysaa in carqalad ah function caadada iyo maqnaanshaha ugxan, sidaas oo kale ayaa rimidda iyo dhalmada noqdo ficil ahaan wax aan macquul aheyn. Daaweynta waxay ka kooban tahay yaraynta heerka, tirtiridda ah sababaha cudurka iyo wareegga soo kabashada.